Paid Clinical Trials in Orlando

Candace Kastanis

Written by Candace Kastanis

Chemistry B.S. | UC Davis | Clinical Lab Technician

Updated & Fact Checked 7/30/26

Clinical Research in Orlando For Money

Orlando’s research runs through two competing hospital systems and a strong pediatric cluster. As of July 2026, 702 studies are actively recruiting in the city, according to ClinicalTrials.gov.

Presently, Orlando’s population is 321,427; or thereabout. According to experts, .005% of the total U.S. population needs to be involved in some sort of clinical research trial in order to advance medical science. Multiply that number by 321,427, and statistically, you can expect at least 1,607 local opportunities.

There are around 43 Clinical Research Organizations (CROs) in or around Orlando, and hundreds more throughout the rest of the state. Just near Orlando proper, you can expect each of those CROs to have, on average, 37 individual trial opportunities. Essentially, if you want to give this a chance, you’ve got options.

When you can make money to help advance science, based just on your personal health and willingness to be a participant, that’s a win-win. Following we’ll explore a few other bits of information to help you narrow down your choice of CRO.

Quick Facts: Paid Clinical Trials in Orlando

  • Actively recruiting studies (July 2026): 702 (ClinicalTrials.gov)
  • Typical compensation: $50–$100 per completed outpatient visit; residential Phase 1 studies pay more (see highest paid clinical trials)
  • Cost to participate: $0 — study care and visits are covered by the sponsor
  • Worth knowing: two hospital systems compete here, so it is worth applying to both AdventHealth and Orlando Health studies
  • Statewide options: paid clinical trials in Florida

Where Orlando trials actually run

We sampled recruiting Orlando studies on ClinicalTrials.gov in July 2026. The sites running the most trials:

Research siteTrials sampled
AdventHealth Orlando77
Orlando Health (incl. Cancer Institute)41
Nemours Children’s Hospital25
Arnold Palmer Hospital for Children25
University of Central Florida18

AdventHealth and Orlando Health between them run most adult research in the metro, while Arnold Palmer Hospital and Nemours Children’s make Orlando unusually strong for pediatric studies. Several of these sit in the Lake Nona medical cluster southeast of downtown, alongside the UCF College of Medicine.

Demographic Data of Orlando is Important to Determine Trial Availability

Demographic data helps drive CRO opportunities locally. So paid clinical trials nearby for healthy volunteers will reflect that data.

Presently, Orlando is approximately 57.42% Caucasian (including Hispanic populations), 24.2% African, and 8.06% of locals have multiple ethnic backgrounds. The median age of the city is 33.5. It is made up of 51.98% female residents, and 48.02% male residents.

Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others
Recruiting
This is an observational longitudinal study to determine the natural history and genotype-phenotype correlations of disease causing mutations in Charcot Marie Tooth disease (CMT) type 1B (CMT1B), 2A (CMT2A), 4A (CMT4A), and 4C (CMT4C). The investigators will also be determine the capability of the newly developed CMT Pediatric Scale (CMT Peds scale) and the Minimal Dataset to measure impairment and perform longitudinal measurements in patients with multiple forms of CMT over a five year window
Gender:
ALL
Ages:
All
Trial Updated:
05/09/2024
Locations: Cedars-Sinai Medical Center, Los Angeles, California +1 locations
Conditions: Charcot Marie Tooth Disease
Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2
Recruiting
This project includes two projects. One is looking for new genes that cause Charcot Marie Tooth disease (CMT). The other is looking for genes that do not cause CMT, but may modify the symptoms a person has.
Gender:
ALL
Ages:
All
Trial Updated:
05/09/2024
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Charcot-Marie-Tooth Disease, Type Ia (Disorder), HMSN
Development of Charcot Marie Tooth Disease (CMT) Pediatric Scale for Children With CMT
Recruiting
The primary goal of this project is to develop and test a Charcot Marie Tooth disease (CMT) Pediatric Scale for use in evaluation in natural history CMT study.
Gender:
ALL
Ages:
21 years and below
Trial Updated:
05/09/2024
Locations: Stanford University, Palo Alto, California
Conditions: Charcot Marie Tooth Disease
Registry Study for Radiation Therapy Outcomes
Recruiting
The purpose of this research study is to collect and analyze information from patients being treated with various forms of radiation therapy.
Gender:
ALL
Ages:
All
Trial Updated:
05/30/2024
Locations: Mayo Clinic, Scottsdale, Arizona
Conditions: Neoplasms
Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation
Recruiting
This study will evaluate the safety of infusion of the investigational cord blood units by carefully documenting all infusion-related problems.
Gender:
ALL
Ages:
All
Trial Updated:
04/17/2024
Locations: Children's of Alabama, Birmingham, Alabama
Conditions: Infusion Reactions
Clinical Trial Evaluating the Efficacy, Safety, and Tolerability of Cariprazine in a Dose-Reduction Paradigm in the Prevention of Relapse in Patients With Schizophrenia
Recruiting
To evaluate the efficacy and safety of cariprazine at a target dose of 4.5 mg/d compared with placebo in prevention of relapse in patients with schizophrenia To evaluate the efficacy and safety of cariprazine at a target dose of 3.0 mg/d compared with placebo in prevention of relapse in patients with schizophrenia who were initially stabilized on a target dose of 4.5 mg/d
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
08/17/2020
Locations: Pillar Clinical Research, Bentonville, Arkansas
Conditions: Schizophrenia
Study of Acalabrutinib (ACP-196) in Combination With Venetoclax (ABT-199), With and Without Obinutuzumab (GA101) Versus Chemoimmunotherapy for Previously Untreated CLL
Recruiting
The purpose of this study is to evaluate the efficacy and safety of acalabrutinib in combination with venetoclax and acalabrutinib in combination with venetoclax with and without obinutuzumab compared to chemoimmunotherapy in subjects with previously untreated CLL.
Gender:
All
Ages:
Between 18 years and 130 years
Trial Updated:
01/14/2022
Locations: Research Site, Fountain Valley, California
Conditions: Chronic Lymphocytic Leukemia
CERENOVUS Neurothrombectomy Devices Registry
Recruiting
A post-market registry evaluating the EmboTrap® Revascularization Device and CERENOVUS Large Bore Catheter/ EMBOVAC Aspiration Catheter in acute ischemic stroke patients with confirmed intracranial large vessel occlusion.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/19/2022
Locations: The University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Cerebral Stroke
Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB054707 in Participants With Normal and Impaired Renal Function and Participants on Hemodialysis
Recruiting
This is a multi-center, open-label, parallel-group study to evaluate oral doses of INCB054707 in participants with varying levels of renal function or impairment.
Gender:
All
Ages:
Between 18 years and 82 years
Trial Updated:
02/17/2023
Locations: Orlando Clinical Research Center, Orlando, Florida
Conditions: Renal Insufficiency, Kidney Diseases
A Study to Compare the Efficacy and Safety of Idecabtagene Vicleucel With Lenalidomide Maintenance Therapy Versus Lenalidomide Maintenance Therapy Alone in Adult Participants With Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation
Recruiting
The purpose of this study is to compare the efficacy, safety, and tolerability of ide-cel with lenalidomide (LEN) maintenance to that of LEN maintenance alone in adult participants with Newly Diagnosed Multiple Myeloma (NDMM) who have achieved a suboptimal response post autologous stem cell transplantation (ASCT).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/01/2024
Locations: Banner MD Anderson Cancer Center, Gilbert, Arizona
Conditions: Multiple Myeloma

Exploring Orlando Diversity to Identify Paid Trial Opportunities

What this means is that the lion’s share of paid clinical trials for healthy volunteers in Orlando will be for Caucasian (including Hispanic) females in their early thirties.

Men in similar categories are a close second but keep in mind, that many CROs have studies that require no gender or ethnic background. Also, there will be more diverse studies conducted locally.

We have compiled the following list of paid clinical trials for healthy volunteers, click the Search All button at the bottom to find more:


Multiple Orlando CROs Have Opportunities for Healthy Participants

In order to identify healthy volunteer paid clinical trials which fit your personal requirements, you will want to explore a few known local research groups conducting trial studies. Here are three to consider if you’re not sure exactly where to start:


Notable Breakthroughs Orlando Can Lay Claim To

There are a lot of things going on in Florida medicine generally, and Orlando has always been one of the most advanced cities in terms of cutting-edge developments. Disney World was designed to be a futuristic city, and it’s in Orlando. So you will find some surprising next-generation research going on in this central Floridian metropolis. Consider these recent breakthroughs for background:


Orlando Paid Clinical Trial FAQs

  • How much do paid clinical trials pay here?

    Most outpatient studies pay $50–$100 per completed visit, plus travel reimbursement. Residential Phase 1 studies pay considerably more. The exact amount appears in the consent form before you enroll.

  • Where in Orlando are most trials located?

    AdventHealth Orlando near downtown and Orlando Health’s campus hold the largest shares, with a growing cluster in Lake Nona that includes Nemours Children’s Hospital and the UCF College of Medicine. Arnold Palmer Hospital covers pediatric research.

  • Are there trials for children in Orlando?

    Yes, more than in most cities this size. Arnold Palmer Hospital for Children and Nemours Children’s Hospital each run substantial pediatric research programs. Parental consent is required, and children old enough to understand also give their own assent.

Orlando CRO Trial Opportunities: Available, and Cutting-Edge

As a state, Florida is trending in more ways than one, and Orlando is one of its most prominent cities. You’re definitely going to find opportunities to supplement income through paid clinical trials in Orlando. There are plenty of studies to choose from across the city, and beyond helping you keep your bank account healthy, they represent tomorrow’s medical solutions.

This means you’re making money, and you’re taking part in research that will very likely change the world in the coming years. At the end of the day, there’s a lot to recommend if you are looking to participate in clinical research studies.