Paid Clinical Trials in Texas

Candace Kastanis

Written by Candace Kastanis

Chemistry B.S. | UC Davis | Clinical Lab Technician

Updated & Fact Checked 7/24/26

Finding Trials in Texas

Paid Clinical Trials in Texas

Everything is bigger in Texas, and that includes clinical research. As of July 2026, more than 4,800 studies are actively recruiting volunteers across the state, according to ClinicalTrials.gov. Most enroll anywhere from dozens to hundreds of participants, and the majority compensate volunteers for time and travel.

About 31 million people call Texas home, and the state’s research footprint matches its size. Houston’s Texas Medical Center is the largest medical complex in the world, and research universities in Dallas, San Antonio, and Austin run hundreds of studies at any given time. If you want to take part in a paid study, the practical question is not whether trials exist near you, but which ones fit your health profile and schedule.

Quick Facts: Paid Clinical Trials in Texas

  • Actively recruiting studies (July 2026): 4,800+ across Texas (ClinicalTrials.gov)
  • Major hubs: Houston (Texas Medical Center, the world’s largest medical complex), Dallas–Fort Worth, San Antonio, and Austin
  • Typical compensation: $50–$100 per completed outpatient visit; residential Phase 1 studies in San Antonio and Austin can pay $3,000–$15,000 (see highest paid clinical trials)
  • Cost to participate: $0 — study care and visits are covered by the sponsor
  • No insurance required for study-related care

2026 Texas Clinical Research Updates

  • Trials expand into rural Texas: CPRIT’s first Rural Clinical Trial Accelerator grants (May 2026) are bringing new cancer trials to East Texas and the Rio Grande Valley, including the Valley’s first comprehensive oncology trials program at UT Health RGV in McAllen.
  • $103 million in new cancer research funding: CPRIT’s 2026 awards sent 30 grants to ten UT institutions, with more than $19 million to MD Anderson for research and recruitment.
  • 4,800+ studies recruiting statewide as of July 2026, per ClinicalTrials.gov.

Expanding Clinical Research Opportunities Throughout Texas

Because of the size of Texas, anyone living in a city of 100k+ people will likely have options. Paid clinical trials nearby for healthy volunteers are likely taking place at whatever CRO is closest to where you are.

A CRO is a Contract Research Organization. These will conduct studies based on those who best fit what is needed in a given location. Often demographics drive the studies performed at a given CRO. So for Texas, there’s going to be some variety. In the south demographics are a bit different than in the north.

Texas is one of the most diverse states in the country, and that matters for research. Trial results need to reflect the people who will eventually use the treatment, so sponsors actively recruit volunteers of different ages and backgrounds. In practice, that means a wider range of Texans qualify for studies than in most states.

Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)
Recruiting
This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important for tumor cell growth and progression. Crizotinib may stop the growth of tumor cells by blocking the ALK protein from working. Crizotinib may be an effective treatment for patients with non-sma... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/29/2024
Locations: Hendrick Medical Center, Abilene, Texas +25 locations
Conditions: ALK Gene Rearrangement, ALK Gene Translocation, ALK Positive, Stage IB Non-Small Cell Lung Carcinoma AJCC v7, Stage II Non-Small Cell Lung Cancer AJCC v7, Stage IIA Non-Small Cell Lung Carcinoma AJCC v7, Stage IIB Non-Small Cell Lung Carcinoma AJCC v7, Stage IIIA Non-Small Cell Lung Cancer AJCC v7
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Recruiting
This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruing simultaneously to a multi-sub-study hybrid Master Protocol (Lung-MAP). The type of cancer trait (biomarker) will determine to which sub-study, within this protocol, a participant will be assigned to compare new targeted cancer therapy, designed to block the growth and spread of cancer, or combinations to standard of... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/12/2025
Locations: Hendrick Medical Center, Abilene, Texas +8 locations
Conditions: Previously Treated Non-Small Cell Lung Cancer
Study to Assess Safety and Efficacy of Tenapanor for Treatment of IBS-C in Pediatric Patients 12 to Less Than 18 Years
Recruiting
This is a randomized, double-blind, placebo-controlled study to assess the efficacy, safety and tolerability of tenapanor (25 mg and 50 mg) in pediatric patients (≥12 and \<18 years old) with IBS-C when administered twice daily (BID) for 12 consecutive weeks.
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
12/12/2024
Locations: Advance Clinical Trial PLLC, Abilene, Texas +7 locations
Conditions: Irritable Bowel Syndrome With Constipation (IBS-C)
Safety and Tolerability of OCU-10-C-110 for Injection in Subjects With Neovascular Age-related Macular Degeneration
Recruiting
Multi-center, open-label, two-part safety assessment following administration of single ascending doses and repeat administration of the HTD of OCU-10-C-110 for Injection in the study eye of participants with nAMD
Gender:
ALL
Ages:
50 years and above
Trial Updated:
03/18/2025
Locations: Retina Research Institute of Texas, Abilene, Texas +1 locations
Conditions: Neovascular Age-related Macular Degeneration (nAMD)
Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Geographic Atrophy
Recruiting
This Phase 3, multicenter, double-masked, parallel-group, placebo-controlled, randomized, fixed-dose clinical study is designed to evaluate the efficacy and safety of tinlarebant (LBS-008) in subjects diagnosed with GA.
Gender:
ALL
Ages:
Between 60 years and 85 years
Trial Updated:
02/12/2025
Locations: Belite Study Site, Abilene, Texas +2 locations
Conditions: Geographic Atrophy
A Prospective, Multicenter, Open-Label, Observational Phase 4 Study to Evaluate Real-World Safety, Tolerability, and Treatment Patterns of Pegcetacoplan (Syfovre) in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration
Recruiting
A Prospective, Multicenter, Open-Label, Observational Phase 4 Study to Evaluate Real-World Safety, Tolerability, and Treatment Patterns of Pegcetacoplan (Syfovre) in Patients with Geographic Atrophy Secondary to Age-Related Macular Degeneration
Gender:
ALL
Ages:
60 years and above
Trial Updated:
05/29/2025
Locations: Integrated Clinical Research (01-024), Abilene, Texas +3 locations
Conditions: Geographic Atrophy
A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of ANX007 in Participants With Geographic Atrophy (GA)
Recruiting
The primary purpose of the study is to determine if IVT injections of ANX007 every month reduce vision loss in participants with GA secondary to age-related macular degeneration (AMD).
Gender:
ALL
Ages:
50 years and above
Trial Updated:
05/08/2025
Locations: Retina Research Institute of Texas, Abilene, Texas +15 locations
Conditions: Geographic Atrophy
Evaluation of the Bexa Breast Examination
Recruiting
Objective: The "Bexa Breast Exam," or "BBE," for the purposes of this study is defined as the use of a Bexa device in conjunction with a portable, focused ultrasound examination to identify and further evaluate abnormal breast masses including cancer. Commercially, this combination of Bexa plus focused ultrasound is called "Bexa Breast ExamTM," and abbreviated as, "BBE." This study compares the Bexa Breast Exam (BBE) to the standard of care (digital breast tomosynthesis) in detecting masses and... Read More
Gender:
FEMALE
Ages:
Between 30 years and 75 years
Trial Updated:
10/16/2024
Locations: Hendrick Health - Vera West Women's Center, Abilene, Texas
Conditions: Breast Cancer
Esprit BTK Post-Approval Study
Recruiting
The Esprit BTK PAS is a prospective, single-arm, multi-center observational study to assess the continued safety and effectiveness of the Esprit™ BTK Everolimus Eluting Resorbable Scaffold System under commercial use, in patients with diseased infrapopliteal lesions causing CLTI (Chronic Limb-Threatening Ischemia) in a real-world setting. The clinical investigation will be conducted at up to 50 sites in the United States (US) and additional sites may be added outside of the US (OUS). Approximate... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/28/2025
Locations: Hendrick Medical Center, Abilene, Texas +3 locations
Conditions: Chronic Limb-Threatening Ischemia
A 2-part Study Consisting of a Multiple Ascending Dose Safety Study in Participants With Macular Edema Following Branch Retinal Vein Occlusion and a Dose-finding Safety and Preliminary Efficacy Study in Participants With Either Diabetic Macular Edema or Neovascular Age-related Macular Degeneration
Recruiting
EYE-TIE-201 is a 2-part study to investigate the safety and effectiveness of a new drug being developed called EYE201. All participants in the study will receive a total of 3 injections of EYE201 into the study eye, spaced at 4 weeks apart. In the first part, termed the multiple ascending dose (MAD) portion of study, the safety of EYE201 will be assessed at increasing doses in branch retinal vein occlusion (BRVO) participants. Approximately 12 participants will be entered in this part of the s... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/19/2025
Locations: Abilene, Texas, Abilene, Texas +9 locations
Conditions: Diabetic Macular Edema (DME), Neovascular Age-related Macular Degeneration (NVAMD), BRVO - Branch Retinal Vein Occlusion

Diverse Population Growth Fuels Paid Clinical Trial Opportunities

Because Texas is one of the most diverse states in the country, paid clinical trials for healthy volunteers are available to a very wide variety of participants. With over 10,000 trials in the state, that means a spread of between 120,000 and 200,000+ opportunities are always available throughout the year.

Texas is also one of the fastest growing states in the country, and research capacity has grown with it. New sites open every year, including in regions that historically had few options.


CROs Across the State Are Seeking Trial Participants

So where do you go to find healthy volunteer paid clinical trials? Again, look for where the CROs are, and explore what they’re offering. Here are a few of the major research centers recruiting Texans right now:


Notable Medical Breakthroughs That Come From Texas

Texas research institutions have produced some substantial medical advances, including:

If you want to be part of the next advance in medical science, Texas is a reasonable place to start looking.


Texas Paid Clinical Trial FAQs

  • How much do paid clinical trials pay in Texas?

    Most outpatient studies in Texas pay $50–$100 per completed visit, plus travel reimbursement. Residential Phase 1 studies, including those at San Antonio’s 200-bed clinical pharmacology unit, commonly pay $3,000–$15,000 for stays of one to four weeks. The exact amount is listed in the consent form before you enroll.

  • Where are most clinical trials in Texas?

    Houston has the largest concentration, anchored by the Texas Medical Center. Dallas–Fort Worth follows with UT Southwestern and a large network of private research sites. San Antonio is a national hub for Phase 1 healthy-volunteer studies, and Austin’s research scene has grown quickly. See our pages for Houston, Dallas, San Antonio, and Austin.

  • Do I need health insurance to join a paid clinical trial in Texas?

    No. Study-related care and visits are paid for by the trial sponsor, and compensation is separate. Ask the study coordinator exactly what is covered before you enroll, especially for care unrelated to the study.

Finding Clinical Trial Opportunities in Texas Perfect For You

Texas is fertile ground for medical breakthroughs, meaning paid clinical trial opportunities are quite numerous. If you need a little extra income, and you want to help the world at the same time, Texas has options in areas like Austin, Dallas, Fort Worth, Houston, and San Antonio.