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Finding Trials in Dallas
There are few cities in the world like Dallas, and even those that are legitimate “peers” can’t really match it. Dallas is a massive, diverse, expanding city, and that expansion extends to the technology being more involved than conventional IT. Medical breakthroughs are huge in Dallas, and it’s easy to find paid clinical trials for healthy volunteers nearby. Right now in Dallas, there are 1,270 clinical trials going on.
Each of those studies will involve multiple participants—well, in most cases. On occasion, unique studies with only one participant may exist. Dallas has 1,325,691 people, presently. Of that number, approximately .005% should, at least according to statistics, be involved in medical trials so that medical science continues to advance. That means there should, at any given time, be 6,628 volunteer trial opportunities available. There’s much potential, and a lot of it has to do with the demographic realities of the region.
Increasing Clinical Research Opportunities in Dallas
You’re most likely to find paid clinical trials nearby for healthy volunteers at CROs, or Clinical Research Organizations. Determining which sorts of trials will best fit you specifically is easier when you’re familiar with the way trials are run. Seldom will you find a CRO conducting trials on something like, say, congenital malaria resistance in a place like Nevada, where the condition is essentially unknown. Volunteer ethnicity and associated medical issues will in part determine available CRO studies. In Dallas, about a third of all locals are Hispanic in terms of culture and background, though genetically most Hispanics are Caucasian, which can make demographic information a bit confusing.
The same link that gave us population earlier has information about Dallas demographics. According to this resource, the median age in Dallas is 32.9, with males at 32.4 and females at 33.5. Females are 50.41% of the population, males are 49.59% of the population. Ethnically, Dallas is 57% Caucasian, 24.3% black, 6.37% two or more races, and 7.6% “other”. The majority of clinical trials will be geared around men and women in their thirties from these ethnic groups. However, there will always be diverse opportunities for those who don’t fit in these categories.
The BrainHealth Project
Recruiting
For an overview of the study and link TO REGISTER please go to -- https://brainhealth.utdallas.edu/programs/the-brainhealth-project/
The BrainHealth Project is a ten-year, longitudinal study focused on identifying determinants of brain health and performance. Participants will have the opportunity to complete semi-annual (twice a year) online assessments to track their performance over time. In between semi-annual assessments, participants will have access to online trainings and ongoing supple... Read More
For an overview of the study and link TO REGISTER please go to -- https://brainhealth.utdallas.edu/programs/the-brainhealth-project/
The BrainHealth Project is a ten-year, longitudinal study focused on identifying determinants of brain health and performance. Participants will have the opportunity to complete semi-annual (twice a year) online assessments to track their performance over time. In between semi-annual assessments, participants will have access to online trainings and ongoing supplemental content regarding ways to optimize brain health and performance. Online one-on-one coaching sessions will be offered to participants to answer questions and provide support in applying the information to their daily lives. A small portion of participants will be invited to participate in the brain imaging portion of this study.
The main objectives are: (i) to characterize lifestyle, cognitive, and behavioral markers related to an individual's cognitive function from adolescent to elderly ages, (ii) to assess the neural/biological determinants predictive of maintenance of brain health, and (iii) to evaluate the impact of available cognitive and lifestyle interventions on improving and maintaining brain health and performance. Read Less
Gender:
ALL
Ages:
Between 18 years and 110 years
Trial Updated:
06/11/2025
Locations: The Center for BrainHealth at The University of Texas at Dallas, Dallas, Texas
The Center for BrainHealth at The University of Texas at Dallas, Dallas, Texas
Conditions: Healthy
Deliver-EE: Evaluating Effects of Meal Delivery
Recruiting
This study will randomly assign 2,300 older adults on waiting lists at fourteen Meals on Wheels programs in Florida, Illinois, Maryland, Tennessee, Texas, North Carolina, South Carolina, and California into two groups who will receive: (a) daily delivery of meals, five days a week or (b) a shipment of 10 frozen meals, every two weeks. Researchers will examine participants' Medicare claims to understand if differences in healthcare utilization occur between the two groups within six months after... Read More
This study will randomly assign 2,300 older adults on waiting lists at fourteen Meals on Wheels programs in Florida, Illinois, Maryland, Tennessee, Texas, North Carolina, South Carolina, and California into two groups who will receive: (a) daily delivery of meals, five days a week or (b) a shipment of 10 frozen meals, every two weeks. Researchers will examine participants' Medicare claims to understand if differences in healthcare utilization occur between the two groups within six months after they start receiving meals. Researchers will also ask participants questions prior to receiving meals, and again at three months, to understand how meals impact their ability to obtain food, their feelings of loneliness, and their overall quality of life. The primary study outcome will be the ratio of days spent in institutional settings (i.e., hospital, nursing home) in the six months after participants begin receiving meals. The secondary outcomes include the ratio of days spent in institutional settings in the three months after participants begin receiving meals, food insecurity, subjective isolation/loneliness, and health-related quality of life. The team will also examine differences in dietary intake between the two groups as an exploratory outcome. Read Less
Gender:
ALL
Ages:
66 years and above
Trial Updated:
04/21/2025
Locations: Meals on Wheels San Diego County, San Diego, California
Visiting Nurse Association of Texas, Dallas, Texas
Conditions: Healthy
Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments, Using Multiomics
Recruiting
The goal of this exploratory study is understand the mechanisms of response to immunotherapy in Non-Small Cell Lung Cancer patients.
The investigators are going to search for correlation between specific biological features and response to immunotherapy, and to use those associations for developing an algorithm enabling to identify patients that could benefit from the immune check inhibitor based anti cancer treatment.
Patients will provide biological samples before and during their treatment,... Read More
The goal of this exploratory study is understand the mechanisms of response to immunotherapy in Non-Small Cell Lung Cancer patients.
The investigators are going to search for correlation between specific biological features and response to immunotherapy, and to use those associations for developing an algorithm enabling to identify patients that could benefit from the immune check inhibitor based anti cancer treatment.
Patients will provide biological samples before and during their treatment, and clinical data will be collected. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/09/2023
Locations: Baylor Scott and White Research Institute, Dallas, Texas
Baylor Scott and White Research Institute, Dallas, Texas
Conditions: Non Small Cell Lung Cancer, Healthy
The Longitudinal Study of Stimulant Use Disorder
Recruiting
This research is a 5-year observational, longitudinal registry study with no treatment or medication provided as part of participation. Individuals with current or lifetime stimulant use disorder, in addition to healthy control individuals, may be eligible to participate in this study. A variety of assessments and tasks including Magnetic Resonance Imaging (MRI), Electroencephalography (EEG), blood draws, urine drug screens, and both self-report and clinician-rated assessments will be used to as... Read More
This research is a 5-year observational, longitudinal registry study with no treatment or medication provided as part of participation. Individuals with current or lifetime stimulant use disorder, in addition to healthy control individuals, may be eligible to participate in this study. A variety of assessments and tasks including Magnetic Resonance Imaging (MRI), Electroencephalography (EEG), blood draws, urine drug screens, and both self-report and clinician-rated assessments will be used to assess biomarkers in this population. This study has a visit schedule of four in-person visits and eight remote visits per year. Read Less
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
12/13/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
UT Southwestern Medical Center, Dallas, Texas
Conditions: Stimulant Use, Stimulant-Related Disorder, Healthy
Gut Oxalate Absorption in Calcium Oxalate Stone Disease
Recruiting
The goal of this clinical trial study is to test if patients with idiopathic calcium oxalate kidney stones have an increased absorption of dietary oxalate, which would lead to increased urinary excretion of oxalate.
The study will recruit adult patients with a history of calcium oxalate kidney stones and healthy volunteers without kidney stones.
Participants will
* ingest fixed diets containing low and moderately high amounts of oxalate for 5 days at a time
* ingest a soluble form of oxalate... Read More
The goal of this clinical trial study is to test if patients with idiopathic calcium oxalate kidney stones have an increased absorption of dietary oxalate, which would lead to increased urinary excretion of oxalate.
The study will recruit adult patients with a history of calcium oxalate kidney stones and healthy volunteers without kidney stones.
Participants will
* ingest fixed diets containing low and moderately high amounts of oxalate for 5 days at a time
* ingest a soluble form of oxalate and sugar preparations to test gut permeability
* collect urine, blood, stool and breath sample during the fixed diets and the soluble oxalate test Read Less
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
05/09/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
UTSW, Dallas, Texas
Conditions: Kidney Stone, Kidney Calculi, Urolithiasis, Urolithiasis, Calcium Oxalate, Nephrolithiasis, Nephrolithiasis, Calcium Oxalate, Oxalate Urolithiasis, Oxaluria, Healthy
A Study of LY3537031 in Overweight, Obese, and Healthy Participants
Recruiting
This is a 4-part study that includes a Part A, Part B, Part C, and Part D. Parts A and D will study the safety and tolerability of the study drug known as LY3537031 in participants who are overweight and obese. Part B and Part C will study the safety and tolerability of LY3537031 in healthy participants. Part C will contain only Japanese and Chinese healthy participants.
Blood tests will be performed to check how much LY3537031 gets into the bloodstream and how long it takes the body to elimina... Read More
This is a 4-part study that includes a Part A, Part B, Part C, and Part D. Parts A and D will study the safety and tolerability of the study drug known as LY3537031 in participants who are overweight and obese. Part B and Part C will study the safety and tolerability of LY3537031 in healthy participants. Part C will contain only Japanese and Chinese healthy participants.
Blood tests will be performed to check how much LY3537031 gets into the bloodstream and how long it takes the body to eliminate it. Body weight will be measured. The study will last approximately 48 weeks excluding a screening period. Read Less
Gender:
ALL
Ages:
Between 22 years and 65 years
Trial Updated:
07/14/2025
Locations: Collaborative Neuroscience Research, LLC, Los Alamitos, California
Fortrea Clinical Research Unit, Dallas, Texas
Conditions: Healthy, Obesity
The Modulatory Effect of Female Sex Hormones on Spinal Neuroplasticity
Recruiting
The goal of this project is to test our central hypothesis that the spinal cord neuroplasticity in females will be modulated by the level of estradiol concentration. under aim 1 we will determine the influence of estradiol fluctuations on spinal circuit excitability post afferent (sensory) mediated subthreshold motor priming in young healthy females and males. We will use an established repetitive peripheral nerve electrical stimulation with a stimulation intensity below the motor threshold to p... Read More
The goal of this project is to test our central hypothesis that the spinal cord neuroplasticity in females will be modulated by the level of estradiol concentration. under aim 1 we will determine the influence of estradiol fluctuations on spinal circuit excitability post afferent (sensory) mediated subthreshold motor priming in young healthy females and males. We will use an established repetitive peripheral nerve electrical stimulation with a stimulation intensity below the motor threshold to prime the spinal motor circuits. under aim 2 we seek to characterize the input output property of spinal circuit excitability after descending drive (motor) mediated priming in young healthy male participants. in aim 3 we will examine the influence of estradiol fluctuations on descending drive mediated motor priming in young healthy females. Read Less
Gender:
ALL
Ages:
Between 18 years and 39 years
Trial Updated:
10/21/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Healthy
A Study of LY4060874 in Healthy Participants
Recruiting
The purpose of this study is to evaluate safety and tolerability of LY4060874 in healthy participants.
Study participation may last up to 22 weeks and up to approximately 18 study visits.
The purpose of this study is to evaluate safety and tolerability of LY4060874 in healthy participants.
Study participation may last up to 22 weeks and up to approximately 18 study visits. Read Less
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
06/27/2025
Locations: Fortrea, Inc., Dallas, Texas
Fortrea, Inc., Dallas, Texas
Conditions: Healthy Participants
Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone Disease
Recruiting
The goal of this clinical trial study is to test if patients with idiopathic calcium oxalate kidney stones have an increased production of oxalate by the body, which would lead to increased urinary excretion of oxalate.
The study will recruit adult patients with a history of calcium oxalate kidney stones and healthy volunteers without kidney stones.
Participants will
ingest fixed diets containing low amounts of oxalate for 5 days ingest a soluble form of glycolate and vitamin C collect urine,... Read More
The goal of this clinical trial study is to test if patients with idiopathic calcium oxalate kidney stones have an increased production of oxalate by the body, which would lead to increased urinary excretion of oxalate.
The study will recruit adult patients with a history of calcium oxalate kidney stones and healthy volunteers without kidney stones.
Participants will
ingest fixed diets containing low amounts of oxalate for 5 days ingest a soluble form of glycolate and vitamin C collect urine, blood, stool during the dietary and oral dosing portions of the study and also collect breath sample during the oral glycolate test Read Less
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/16/2025
Locations: United States, Alabama University of Alabama at Birmingham, Birmingham, Alabama
University of Texas South Western Medical Center, Dallas, Texas
Conditions: Kidney Stones, Kidney Calculi, Urolithiasis, Urolithiasis, Calcium Oxalate, Nephrolithiasis, Nephrolithiasis, Calcium Oxalate, Oxalate Urolithiasis, Healthy, Healthy Volunteer
A Study of LY3867070 in Healthy Participants
Recruiting
The purpose of this study is to evaluate how well LY3867070 is tolerated and what side effects may occur in healthy participants. The study drug will be administered orally. Blood tests will be performed to investigate how the body processes the study drug and how the study drug affects the body.
The purpose of this study is to evaluate how well LY3867070 is tolerated and what side effects may occur in healthy participants. The study drug will be administered orally. Blood tests will be performed to investigate how the body processes the study drug and how the study drug affects the body. Read Less
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
06/13/2025
Locations: Anaheim Clinical Trials, LLC, Anaheim, California
Fortrea Clinical Research Unit, Dallas, Texas
Conditions: Healthy
Diverse Population Supports Paid Clinical Trial Opportunities
Because of the diversity of Texas, and Dallas in particular, paid clinical trials for healthy volunteers won’t be limited demographically, they’ll just align with the data. As noted earlier, there should be 6,000+ opportunities available at any given moment throughout the city. You’ve just got to find them. Whoever you are, and wherever you live in the city, there’s a CRO nearby that can help.
CROs in Dallas Seek Trial Participants
So which CROs are offering healthy volunteer paid clinical trials? Well, throughout the state, hundreds of them. In Dallas particularly, several CROs you might want to look into for such opportunities include:
Notable Medical Breakthroughs Centered in Dallas
Dallas is a regional leader for medicine in Texas, in the United States, and globally. Some of the world’s best scientific advances have developed out of studies like those involving paid clinical research trials. You can be a part of that. Here are some trending medical news items from the region to think about:
- Anti-PCSK9 Antibody Breakthroughs
- A Global Leader in Medical Research and Innovation
- Regional Discoveries Make the Region a Medical Destination
Clinical Trial Opportunities in Dallas: Close at Hand
Those interested in helping advance medicine who need to supplement income will find clear opportunities in Dallas. The community is diverse, growing, and a regional center for medical advancement. There are likely paid trials near you.