Paid Clinical Trials in Ohio

Candace Kastanis

Written by Candace Kastanis

Chemistry B.S. | UC Davis | Clinical Lab Technician

Updated & Fact Checked 7/25/26

Health Volunteer Paid Trials in Ohio

Paid Clinical Trials in Ohio

As of July 2026, 3,142 studies are actively recruiting volunteers in Ohio, according to ClinicalTrials.gov. Cleveland Clinic runs the state’s largest program, Ohio State’s James Cancer Hospital anchors Columbus, and Ohio is one of the few states with two nationally ranked children’s research hospitals: Cincinnati Children’s and Nationwide Children’s in Columbus.

Ohio has approximately 411 CROs. Now such organizations usually conduct multiple trials with multiple participants in multiple test and control groups. To get an idea of what opportunities are available in Ohio, you want to factor in two things.

That means each CRO likely provides opportunities for 144 people. Some will have more options, and some will have fewer, but you’ll be able to find something in Ohio if you’re interested in this sort of opportunity. In order to determine which CRO options are best, we’ll explore a few other pieces of information to narrow things down.

Quick Facts: Paid Clinical Trials in Ohio

  • Actively recruiting studies (July 2026): 3,142 (ClinicalTrials.gov)
  • Typical compensation: $50–$100 per completed outpatient visit; residential Phase 1 studies pay more (see highest paid clinical trials)
  • Cost to participate: $0 — study care and visits are covered by the sponsor
  • Worth knowing: Two nationally ranked children’s research hospitals — pediatric and family studies are an Ohio strength

What’s being studied in Ohio right now

We sampled recruiting Ohio studies on ClinicalTrials.gov in July 2026. The most active sites and most-studied conditions:

Most active research sitesMost-studied conditions
Cleveland Clinic (161 listings)Breast and ovarian cancer
Ohio State University / James Cancer Hospital, Columbus (121)Advanced solid tumors
Cincinnati Children’s Hospital (82)Endometrial cancer
Nationwide Children’s Hospital, Columbus (56)Heart failure

Ohio’s three metro anchors mean most residents are within an hour or two of a major research center, and its two children’s hospitals make it one of the strongest states for pediatric studies.

Demographic Data Shows Clinical Trial Availability

A great way to find paid clinical trials nearby for healthy volunteers is to explore local demographic realities. This will help determine what sort of people CROs are likely to need. They’ve got to work with the groups that are available to them, demographics help reveal this data. In Ohio, Caucasians are 80.47% of the population, Black or African populations represent 12.36% of the state, and those of two or more ethnicities are 3.56% of the population. The median age in Ohio is 38, women are 50.99% of the population, and men are 49.01% of the population.

Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation
Recruiting
This study will evaluate the safety of infusion of the investigational cord blood units by carefully documenting all infusion-related problems.
Gender:
ALL
Ages:
All
Trial Updated:
04/17/2024
Locations: Akron Children's Hospital, Akron, Ohio +5 locations
Conditions: Infusion Reactions
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
Recruiting
The North American Mitochondrial Disease Consortium (NAMDC) maintains a patient contact registry and tissue biorepository for patients with mitochondrial disorders.
Gender:
ALL
Ages:
All
Trial Updated:
09/03/2024
Locations: Akron Children's Hospital, Akron, Ohio +2 locations
Conditions: Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes, Deletion and Duplication of Mitochondrial DNA
Pediatric Vasculitis Initiative
Recruiting
Childhood chronic vasculitis describes a group of rare life-threatening diseases that have in common inflammation of blood vessels in vital organs such as kidneys, lungs and brain. Most knowledge about them comes from adult patients. Severe disease requires aggressive life-saving treatments with steroids and some cancer drugs which can themselves cause damage, and increase risks of cancer and severe infections. Conversely, milder disease can be treated with less toxic drugs. Different classifica... Read More
Gender:
ALL
Ages:
20 years and below
Trial Updated:
11/27/2023
Locations: Akron Children's Hospital, Akron, Ohio
Conditions: Wegeners Granulomatosis (Granulomatosis With Polyangiitis), Microscopic Polyangiitis, Polyarteritis Nodosa, Takayasu Arteritis, Primary CNS Vasculitis, Unclassified Vasculitis, Eosinophilic Granulomatosis With Polyangiitis
Donor-Derived Viral Specific T-cells (VSTs)
Recruiting
In this research study, the investigators want to learn more about the use of donor-derived viral specific T-cells (VSTs) to treat viral infections that occur after allogeneic stem cell transplant. A viral specific T cell is a T lymphocyte (a type of white blood cell) that kills cells that are infected (particularly with viruses). Allogeneic means the stem cells come from another person. These VSTs are cells specially designed to fight the virus infections that can happen after a bone marrow tra... Read More
Gender:
ALL
Ages:
4 weeks and above
Trial Updated:
12/09/2024
Locations: Akron Children's Hospital, Akron, Ohio +2 locations
Conditions: Allogeneic Stem Cell Transplant, Viral Infection, Viral Reactivation
Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)
Recruiting
This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important for tumor cell growth and progression. Crizotinib may stop the growth of tumor cells by blocking the ALK protein from working. Crizotinib may be an effective treatment for patients with non-sma... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/29/2024
Locations: Cleveland Clinic Akron General, Akron, Ohio +101 locations
Conditions: ALK Gene Rearrangement, ALK Gene Translocation, ALK Positive, Stage IB Non-Small Cell Lung Carcinoma AJCC v7, Stage II Non-Small Cell Lung Cancer AJCC v7, Stage IIA Non-Small Cell Lung Carcinoma AJCC v7, Stage IIB Non-Small Cell Lung Carcinoma AJCC v7, Stage IIIA Non-Small Cell Lung Cancer AJCC v7
Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs
Recruiting
Advanced airway interventions are common high risk, high stakes events for children in intensive care units (ICU) and emergency departments (ED), with risk for life and health threatening consequences.
Gender:
ALL
Ages:
All
Trial Updated:
01/21/2025
Locations: Akron Children's Hospital, Akron, Ohio +3 locations
Conditions: Failed or Difficult Intubation, Sequela, Intubation; Difficult, Intubation Complication
Third Party Viral Specific T-cells (VSTs)
Recruiting
The purpose of this study is to demonstrate that viral specific T-cells (a type of white blood cell) can be generated from an unrelated donor and given safely to patients with viral infections.
Gender:
ALL
Ages:
2 days and above
Trial Updated:
12/09/2024
Locations: Akron Children's Hospital, Akron, Ohio +3 locations
Conditions: Viral Infection, Viral Reactivation, Infection in an Immunocompromised Host
Quality of Pediatric Resuscitation in a Multicenter Collaborative
Recruiting
This is a prospective, observational, multi-center cohort study of pediatric cardiac arrests. The purpose of the study is to determine the association between chest compression mechanics (rate, depth, flow fraction, compression release) and patient outcomes. In addition, the investigators will determine the association of post cardiac arrest care with patient outcomes.
Gender:
ALL
Ages:
Between 0 years and 17 years
Trial Updated:
04/12/2024
Locations: Akron Children's, Akron, Ohio +2 locations
Conditions: Cardiac Arrest, Cardiopulmonary Arrest
The Myelin Disorders Biorepository Project
Recruiting
The Myelin Disorders Biorepository Project (MDBP) seeks to collect and analyze clinical data and biological samples from leukodystrophy patients worldwide to support ongoing and future research projects. The MDBP is one of the world's largest leukodystrophy biorepositories, having enrolled nearly 2,000 affected individuals since it was launched over a decade ago. Researchers working in the biorepository hope to use these materials to uncover new genetic etiologies for various leukodystrophies,... Read More
Gender:
ALL
Ages:
All
Trial Updated:
11/15/2024
Locations: Akron Children's Hospital, Akron, Ohio +1 locations
Conditions: Leukodystrophy, White Matter Disease, Leukoencephalopathies, Aicardi Goutieres Syndrome, Metachromatic Leukodystrophy, TUBB4A-Related Leukodystrophy, 4H Syndrome, Krabbe Disease, Alexander Disease, Pelizaeus-Merzbacher Disease, Adrenoleukodystrophy, Adrenomyeloneuropathy, Multiple Sulfatase Deficiency, Megalencephalic Leukoencephalopathy With Subcortical Cysts, Vanishing White Matter Disease, Cockayne Syndrome, Labrune Syndrome, ADLD, Gangliosidoses, Peroxisomal Biogenesis Disorder, AMN, ALD, ALD Gene Mutation, ALD (Adrenoleukodystrophy), X-linked Adrenoleukodystrophy, X-ALD, AGS, Alexanders Leukodystrophy, AxD, Canavan Disease, CTX, Cerebrotendinous Xanthomatoses, GALC Deficiency, Globoid Leukodystrophy, H-ABC - Hypomyelination, Atrophy of Basal Ganglia and Cerebellum, HBSL, HBSL - Hypomyelination, Brain Stem, Spinal Cord, Leg Spasticity, LBSL, Leukoencephalopathy With Brain Stem and Spinal Cord Involvement and High Lactate Syndrome (Disorder), Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation, ALSP, CSF1R Gene Mutation, HCC - Hypomyelination and Congenital Cataract, MLC1, MLD, PMD, PLP1 Null Syndrome, PLP1 Gene Duplication | Blood or Tissue | Mutations, Pelizaeus Merzbacher Like Disease, Zellweger Syndrome, Refsum Disease, Salla Disease, Sialic Storage Disease, Sjögren, Sjogren-Larsson Syndrome, Van Der Knapp Disease, Charcot-Marie-Tooth, CMT, Mct8 (Slc16A2)-Specific Thyroid Hormone Cell Transporter Deficiency, Allan-Herndon-Dudley Syndrome, Cadasil, GM2 Gangliosidosis, BPAN, LCC, Mucopolysaccharidoses, TBCK-Related Intellectual Disability Syndrome
The PREDICT Registry:
Recruiting
This is a prospective, non-interventional (observational) cohort study conducted within the medical network of the participating investigators and institutions. Patients meeting the eligibility criteria (see below) will be eligible for participation and the investigators will obtain written informed consent. A central Institutional Review Board (IRB), WCG IRB, will approve the protocol and each participating institution.
Gender:
FEMALE
Ages:
Between 30 years and 85 years
Trial Updated:
09/03/2024
Locations: Cleveland Clinic Akron General, Akron, Ohio +2 locations
Conditions: DCIS

Interpreting Ohio Demographic Information to Find Paid Trials

What we can determine from this information is that in Ohio, paid clinical trials for healthy volunteers will be most available for Caucasian women in their late thirties. However, with many trials, a general diversity of participants is needed; so if you don’t find the study you’re looking for right away, keep looking.


Ohio CROs Healthy Participants Might Explore

Certainly, you’ve got a lot of options to choose from in Ohio. Here are several healthy volunteer paid clinical trials from different parts of the state to give you an idea of what to look for:


Medical Trends in Ohio That Influence the Science

There are a lot of advantages to participating in paid clinical trials; you can be part of history, contribute to science, and put a little money in your pocket at the same time. Just to give you an idea what you might be able to be involved with, here are a few medical contributions from the state of Ohio:


Ohio Paid Clinical Trial FAQs

  • How much do paid clinical trials pay in Ohio?

    Most outpatient studies in Ohio pay $50–$100 per completed visit, plus travel reimbursement. The exact amount appears in the consent form before you enroll.

  • Where are most clinical trials in Ohio?

    Cleveland leads with Cleveland Clinic and University Hospitals, Columbus follows with Ohio State and Nationwide Children’s, and Cincinnati rounds out the big three with Cincinnati Children’s and UC Health.

  • Can my child participate in a paid study in Ohio?

    Yes, with parental consent. Cincinnati Children’s and Nationwide Children’s are among the most active pediatric research centers in the country, and studies compensate families for time and travel. Children old enough to understand also give their own assent.

Ohio Trial Opportunities Healthy Volunteers Might Consider

At the end of the day, you’ve got options. If you’re healthy and want to make money historically contributing to science, CROs in Ohio have some prime clinical research opportunities to explore.