Paid Clinical Trials in Tennessee

Candace Kastanis

Written by Candace Kastanis

Chemistry B.S. | UC Davis | Clinical Lab Technician

Updated & Fact Checked 7/25/26

how to find clinical trials

As of July 2026, 1,963 studies are actively recruiting volunteers in Tennessee, according to ClinicalTrials.gov. Vanderbilt University Medical Center in Nashville runs the state’s largest program, St. Jude Children’s Research Hospital makes Memphis a global center for pediatric research, and Sarah Cannon Research Institute gives Nashville one of the country’s biggest industry-run oncology trial networks.

If you’re trying to find paid clinical trials for healthy volunteers nearby, odds are, you can find them closer than you may have realized in Tennessee. Clinical Research Organizations, or CROs, commonly conduct studies which require volunteers. In Tennessee, there are at least 124 organizations conducting such research presently, and likely more to come.

That may not initially sound like a lot, but each individual organization will conduct experiments requiring multiple participants. Experts estimate 1 in 200, (approximately half of one percent) of the population needs to be involved in such studies at all times to advance the science. While experimentation won’t necessarily follow that statistical distribution nationwide, where there are larger populations, it’s more likely such averages will apply.

In fact, probably more opportunities will exist in larger, more historical locations. Whatever the case, assuming a 1 in 200 distribution of paid volunteer opportunities for healthy participants, Tennessee’s approximately 7,023,788 population indicates something in the neighborhood of 35,118 options statewide; or 283 individual opportunities per study. To narrow things down further, we’ll need to look into demographic data.

Quick Facts: Paid Clinical Trials in Tennessee

  • Actively recruiting studies (July 2026): 1,963 (ClinicalTrials.gov)
  • Typical compensation: $50–$100 per completed outpatient visit; residential Phase 1 studies pay more (see highest paid clinical trials)
  • Cost to participate: $0 — study care and visits are covered by the sponsor
  • Worth knowing: St. Jude in Memphis never bills families for treatment, travel, housing, or food during childhood cancer research

What’s being studied in Tennessee right now

We sampled recruiting Tennessee studies on ClinicalTrials.gov in July 2026. The most active sites and most-studied conditions:

Most active research sitesMost-studied conditions
Vanderbilt University Medical Center, Nashville (224 listings)Breast cancer
Sarah Cannon Research Institute / SCRI Oncology, Nashville (96)Advanced solid tumors
St. Jude Children’s Research Hospital, Memphis (57)Endometrial cancer
Regional systems in Knoxville and ChattanoogaColorectal cancer

Nashville is one of the few US cities where a commercial research network (Sarah Cannon, part of HCA) rivals the academic center in trial volume, which means more industry-sponsored studies recruiting here than in most states.

Demographic Data Helps Reveal Trial Availability in Tennessee

In Tennessee, 76.73% of the total population is white, 16.67% is black or of African descent, and only 2.94% of the population have two or more races in their ethnic background. 51.21% of the population is female, 48.79% are male. The median age is 38.8 years. So paid clinical trials nearby for healthy volunteers will likely trail this data.

Follow-up Visit of High Risk Infants
Recruiting
The NICHD Neonatal Research Network's Follow-Up study is a multi-center cohort in which surviving extremely low birth-weight infants born in participating network centers receive neurodevelopmental, neurosensory and functional assessments at 22-26 months corrected age (Infants born prior to July 1, 2012 were seen at 18-22 months corrected age). Data regarding pregnancy and neonatal outcome are collected prospectively. The goal is to identify potential maternal and neonatal risk factors that may... Read More
Gender:
ALL
Ages:
Between 18 months and 26 months
Trial Updated:
02/11/2025
Locations: University of Tennessee, Memphis, Tennessee
Conditions: Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Consent for Use of Stored Patient Specimens for Future Testing
Recruiting
The purpose of this study is to obtain informed consent to use stored human biological materials (HBM) (e.g., blood and other tissues) for future studies that may include genetic testing.
Gender:
ALL
Ages:
All
Trial Updated:
09/20/2024
Locations: Vanderbilt Univ Med Ctr, Nashville, Tennessee
Conditions: HIV Infections
Generic Database of Very Low Birth Weight Infants
Recruiting
The Generic Database (GDB) is a registry of very low birth weight infants born alive in NICHD Neonatal Research Network (NRN) centers. The GDB collects observational baseline data on both mothers and infants, and the therapies used and outcomes of the infants. The information collected is not specific to a disease or treatment (i.e., it is "generic"). Data are analyzed to find associations and trends between baseline information, treatments, and infant outcome, and to develop future NRN trials.
Gender:
ALL
Ages:
14 days and below
Trial Updated:
02/11/2025
Locations: University of Tennessee, Memphis, Tennessee
Conditions: Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
TrialNet Pathway to Prevention of T1D
Recruiting
Rationale: The accrual of data from the laboratory and from epidemiologic and prevention trials has improved the understanding of the etiology and pathogenesis of type 1 diabetes mellitus (T1DM). Genetic and immunologic factors play a key role in the development of T1DM, and characterization of the early metabolic abnormalities in T1DM is steadily increasing. However, information regarding the natural history of T1DM remains incomplete. The TrialNet Natural History Study of the Development of T... Read More
Gender:
ALL
Ages:
Between 2 years and 45 years
Trial Updated:
06/30/2025
Locations: Vanderbilt University, Nashville, Tennessee
Conditions: Diabetes Mellitus, Type 1
Spinal Cord Injury Registry - North American Clinical Trials Network
Recruiting
The NACTN Spinal Cord Injury Registry is a network of clinical centers collecting de-identified data from patients admitted through the Emergency Department of a NACTN center at the time of injury with an initial (first time) spinal cord injury (SCI). Information will be collected on the natural history of SCI and course of treatment through the first 12 months from the date of injury or long as medically indicated. Data collected includes imaging information from CT or MRI scans, neurological a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/22/2020
Locations: Hamid Shah, MD, Nashville, Tennessee
Conditions: Spinal Cord Injury
Fabry Disease Registry & Pregnancy Sub-registry
Recruiting
The Fabry Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Fabry disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The primary objectives of the Registry are: * To enhance the understanding of the variability, progression, and natural history of F... Read More
Gender:
ALL
Ages:
All
Trial Updated:
08/07/2025
Locations: Vanderbilt University Hospital-Pediatrics- Site Number : 840049, Nashville, Tennessee
Conditions: Fabry Disease
Pompe Disease Registry Protocol
Recruiting
The Pompe Registry is a global, multicenter, international, longitudinal, observational, and voluntary program for patients with Pompe disease, designed to track the disease's natural history and outcomes in patients, both treated and not. Data from the Registry are also used to fulfill various global regulatory commitments, to support product development/reimbursement, and for other research and non-research related purposes. The objectives of the Registry are: * To enhance understanding of t... Read More
Gender:
ALL
Ages:
All
Trial Updated:
08/06/2025
Locations: Vanderbilt University Hospital-Pediatrics- Site Number : 840049, Nashville, Tennessee
Conditions: Glycogen Storage Disease Type II, Pompe Disease
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
Recruiting
The main purpose of the Product Performance Report (formerly referred to as System Longevity Study) is to evaluate long-term performance of Medtronic market-released cardiac rhythm products by analyzing product survival probabilities.
Gender:
ALL
Ages:
All
Trial Updated:
07/29/2025
Locations: Not set, Germantown, Tennessee +1 locations
Conditions: Arrhythmia, Bradycardia, Heart Failure, Sinus Tachycardia
Providing Access to the Visual Environment
Recruiting
Providing Access to the Visual Environment is a pediatric low vision grant which has the ability to provide comprehensive, interdisciplinary low vision rehabilitation services to every child in Tennessee with a vision impairment. Children, ages 3-21, with best-corrected vision of 20/50 or worse in the better seeing eye are prescribed optical devices to improve their visual functioning and trained to use the devices.
Gender:
ALL
Ages:
Between 3 years and 21 years
Trial Updated:
07/02/2025
Locations: Saige Wilkins, Nashville, Tennessee
Conditions: Vision Impairment
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry
Recruiting
The ICGG Gaucher Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Gaucher disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The objectives of the Registry are: * To enhance understanding of the variability, progression, identification, and natural... Read More
Gender:
ALL
Ages:
All
Trial Updated:
08/12/2025
Locations: Vanderbilt University Hospital-Pediatrics- Site Number : 840049, Nashville, Tennessee
Conditions: Gaucher Disease, Cerebroside Lipidosis Syndrome, Glucocerebrosidase Deficiency Disease, Glucosylceramide Beta-Glucosidase Deficiency Disease

Interpreting Tennessee Demographic Data to Find Paid Trials

Definitely, expect there to be niche paid clinical trials for healthy volunteers in Tennessee. Primarily, though, options will be aimed at adults in their late thirties, with an emphasis on female participants. For many studies, there will be a need for participants who are as categorically different as possible, so keep that in mind as well.


Tennessee CROs With Opportunities for Healthy Participants

To help you find options in healthy volunteer paid clinical trials, a good starting point is researching statewide CROs. You’ve got options throughout Tennessee. Here are several to consider from different regions:


Notable Medical Trends in Tennessee

One of the great advantages of participating in paid clinical research trials for healthy volunteers is advancing medicine, which in turn makes you part of history. As the health industry continues to blossom in Tennessee, there have been changes not only to the business climate, but at the government level as well. You could be involved in advances such as these:


Tennessee Paid Clinical Trial FAQs

  • How much do paid clinical trials pay in Tennessee?

    Most outpatient studies in Tennessee pay $50–$100 per completed visit, plus travel reimbursement. The exact amount appears in the consent form before you enroll.

  • Where are most clinical trials in Tennessee?

    Nashville leads with Vanderbilt and Sarah Cannon Research Institute, Memphis follows with St. Jude and the University of Tennessee Health Science Center, and Knoxville has options through the University of Tennessee Medical Center.

  • What makes St. Jude different from other research hospitals?

    St. Jude treats children with cancer and other catastrophic diseases at no cost to families. Treatment, travel, housing, and food are all covered, and most of its patients take part in research. Families are never asked to pay for participation.

Tennessee CRO Trial Opportunities are There For Healthy Volunteers

Tennessee is becoming established in a new area of American culture: the healthcare industry. Not only are there lots of opportunities for individuals seeking additional income, and a role in history as it’s made, but it’s to be expected these trends will continue. Nashville is one of America’s most popular cities right now, and there are some amazing trends in Tennessee overall. So if you’ve never participated in a clinical study, and you are in Tennessee, you might as well see if there are any trials going on in your area, such as Knoxville.