Contents
- 1 Research For Healthy Volunteers
- 2 Demographic Data Helps Identify Trial Availability in Knoxville
- 3 Interpreting Knoxville Demographic Data to Find Paid Trials
- 4 Knoxville CROs With Opportunities for Healthy Participants
- 5 Notable Medical Trends in Knoxville
- 6 Knoxville Paid Clinical Trial FAQs
- 7 Knoxville CRO Trial Opportunities For Healthy Volunteers
Research For Healthy Volunteers

Knoxville is a smaller research market, and it is worth knowing that before you start looking. As of July 2026, 220 studies are actively recruiting in the city, according to ClinicalTrials.gov — a fraction of what Nashville runs, though the studies here tend to have less competition for spots.
If you’re trying to find new ways to supplement your income, you might want to consider paid clinical trials for healthy volunteers nearby. Knoxville has 28 facilities conducting paid clinical research. Usually, these facilities are Clinical Research Organizations or CROs. CROs have to conduct multiple studies, and generally, these studies involve multiple participants.
Certainly, some may only require one or two volunteers, but in many scenarios, a test group and a control group of dozens or hundreds are necessary. It’s estimated for American medicine to continue advancing progressively over time, approximately 1 in 200 people, or half of one percent, need to be involved in some sort of clinical research throughout the year.
So for Knoxville, that means you should expect a range of between 965 and 4,500 individual opportunities between the center of the city and facilities throughout the greater metro area. That means each of those 28 facilities, according to the stats, should have opportunities for around 34 to 160 people per CRO. In order to clarify the picture of local opportunities further, we’ll explore demographic data next.
Quick Facts: Paid Clinical Trials in Knoxville
- Actively recruiting studies (July 2026): 220 (ClinicalTrials.gov)
- Typical compensation: $50–$100 per completed outpatient visit; residential Phase 1 studies pay more (see highest paid clinical trials)
- Cost to participate: $0 — study care and visits are covered by the sponsor
- Worth knowing: fewer studies run here than in Nashville, but less competition for the spots that exist
- Statewide options: paid clinical trials in Tennessee
Where Knoxville trials actually run
We sampled recruiting Knoxville studies on ClinicalTrials.gov in July 2026. The sites running the most trials:
| Research site | Trials sampled |
|---|---|
| University of Tennessee Medical Center and UT Knoxville | 64 |
| East Tennessee Children’s Hospital | 24 |
| Tennessee Cancer Specialists | 9 |
| Alliance for Multispecialty Research (AMR) | 9 |
The University of Tennessee Medical Center anchors adult research and East Tennessee Children’s Hospital covers pediatrics. Tennessee Cancer Specialists and AMR run industry-sponsored studies, which tend to move faster through screening. For a wider selection, Nashville is about 180 miles west and Vanderbilt runs one of the largest programs in the South.
Demographic Data Helps Identify Trial Availability in Knoxville
Knoxville ethnicity is, according to recent statistics, 75.63% white, and 16.94% black or African. Meanwhile, 3.86% of the population have two or more races in their ethnic background. The remaining population is minimally diverse, though Tennessee does have a certain level of diversity. In terms of male/female distribution, 51.98% of the population is female, and 48.02% is male. The median age is 32.9. As you seek paid clinical trials nearby for healthy volunteers, keep this data in mind.
Interpreting Knoxville Demographic Data to Find Paid Trials
Essentially, CROs are going to use whatever cultural elements define the area where they’re established, except in certain special circumstances. For Knoxville, paid clinical trials for healthy volunteers are going to predominantly involve adults in their early thirties. Keep in mind, most studies require data that incorporates as many relevant variables as possible, meaning many CROs seek out diverse volunteers. In a nutshell, there are 900 to 4,500 opportunities available for anyone who is willing and healthy in Knoxville. Adults in their early thirties will have the best options.
Knoxville CROs With Opportunities for Healthy Participants
In order to help you in your search for healthy volunteer paid clinical trials, here are several options from different areas of Knoxville that offer opportunities:
Notable Medical Trends in Knoxville
Quite a few different signposts on the trail of history were driven into the historical ground by the people of Knoxville, Tennessee. The city has made contributions to medical sciences in its past, advanced tech is being used in the present, and researchers are paving the way to the future:
- Discoveries About Medicinal Health Stretching Back to Knoxville’s Foundation
- Advanced Technology in Current Use to Make Birth Safer at Knoxville Medical Center
- Graduate Level Research at the University of Tennessee, Knoxville
Knoxville Paid Clinical Trial FAQs
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How much do paid clinical trials pay here?
Most outpatient studies pay $50–$100 per completed visit, plus travel reimbursement. Residential Phase 1 studies pay considerably more. The exact amount appears in the consent form before you enroll.
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What should I do if I cannot find a Knoxville study that fits?
Nashville is roughly 180 miles west and runs close to 2,000 recruiting studies through Vanderbilt, Sarah Cannon, and other centers. Many sponsors reimburse travel, and some studies need only a few in-person visits, so a Nashville trial can still be workable.
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Are there industry-sponsored studies in Knoxville?
Yes. Dedicated research companies including Alliance for Multispecialty Research and Tennessee Cancer Specialists run sponsor-funded trials in the area. These often screen faster than academic centers and cover conditions like diabetes, dermatology, and respiratory illness.
Knoxville CRO Trial Opportunities For Healthy Volunteers
If you are trying to find clinical research opportunities for healthy volunteers in Knoxville, Tennessee, you’ve got options. Reach out and be a part of history.
