Paid Clinical Trials in Houston

Candace Kastanis

Written by Candace Kastanis

Chemistry B.S. | UC Davis | Clinical Lab Technician

Updated & Fact Checked 7/30/26

Finding Trials in Houston

Houston runs more clinical trials than most states. As of July 2026, 2,855 studies are actively recruiting in the city, according to ClinicalTrials.gov — a direct result of the Texas Medical Center, the largest medical complex in the world, sitting in the middle of town.

Paid clinical trials for healthy volunteers in Houston put participants at the heart of world-class medical advancement. In Texas, everything is bigger. Houston is, perhaps, the archetypical metropolis truly fleshing out this perspective. When you consider that about 1 in 8 workers in Houston proper (excluding metropolitan areas) are involved in the healthcare industry, it’s almost like you’ve got the “pick of the litter”, as the saying goes, when it comes to paid clinical trial options.

Quick Facts: Paid Clinical Trials in Houston

  • Actively recruiting studies (July 2026): 2,855 in Houston (ClinicalTrials.gov)
  • Typical compensation: $50–$100 per completed outpatient visit; residential Phase 1 studies pay more (see highest paid clinical trials)
  • Cost to participate: $0 — study care and visits are covered by the sponsor
  • Worth knowing: the Texas Medical Center campus holds most of the city’s trials within a few square miles, and the METRORail Red Line stops there
  • Statewide options: see paid clinical trials in Texas

Where Houston trials actually run

We sampled recruiting Houston studies on ClinicalTrials.gov in July 2026. The sites running the most trials:

Research siteTrials sampled
MD Anderson Cancer Center145
Baylor College of Medicine35
UTHealth Houston31
Houston Methodist Hospital18

MD Anderson alone accounts for roughly a third of sampled Houston trials, which makes the city one of the best places in the country to find a cancer study. Non-cancer research runs through Baylor, UTHealth, and Houston Methodist.

Steadily Expanding Demographics

Including the metropolitan area surrounding the city, there are approximately 7.12 million people in Houston. Any city that size is going to need strong healthcare to sustain the population and advance science. Collaterally, Houston has one of the world’s largest medical complexes, employing 376,000+ healthcare workers, and providing ample opportunity for healthy volunteer paid clinical trials. The key word is “healthy volunteer”. If you’ve got your health and a little boldness, you can pick and choose varying trials, collaterally advancing science while being compensated for your time. Those seeking work in this industry will find it. Paid clinical trials for healthy volunteers are everywhere.

The population of Houston is steadily growing even in the wake of 2020’s health crisis. Houston is one of Texas’ most diverse cities, with only about 51% of the population being caucasian. What this means is that healthcare isn’t only diverse, but by dint of necessity it must be diverse, and new healthcare options for a diverse population are consistently being researched.
Essentially, if you’re local and doing a search engine query for “paid clinical trials near me for healthy volunteers”, you’re going to find endless options in Houston. Whether you just need a little additional income or you’re trying to help healthcare professionals advance medical science, Houston is fertile ground.

Sugammadex vs. Placebo to Prevent Residual Neuromuscular Block in the Post---Anesthesia Care Unit
Recruiting
The Primary objective of this study is to determine whether patients who receive sugammadex immediately after tracheal extubation will exhibit a decrease in the incidence of postoperative residual paralysis and an associated decrease in the incidence of postoperative respiratory depression (which can precede critical respiratory events, CRE). The Secondary objectives are to: a) determine whether patients receiving sugammadex will have a normal TOF ratio (>0.90) indicative of full neuromuscular... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
07/31/2019
Locations: Memorial Hermann Hospital, Houston, Texas
Conditions: Neuromuscular Blockade, Respiratory Insufficiency
Clinical Trial Evaluating the Efficacy, Safety, and Tolerability of Cariprazine in a Dose-Reduction Paradigm in the Prevention of Relapse in Patients With Schizophrenia
Recruiting
To evaluate the efficacy and safety of cariprazine at a target dose of 4.5 mg/d compared with placebo in prevention of relapse in patients with schizophrenia To evaluate the efficacy and safety of cariprazine at a target dose of 3.0 mg/d compared with placebo in prevention of relapse in patients with schizophrenia who were initially stabilized on a target dose of 4.5 mg/d
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
08/17/2020
Locations: Pillar Clinical Research, Bentonville, Arkansas
Conditions: Schizophrenia
An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis
Recruiting
The present study D5272C00001 (Legacy # 3151-201-008) seeks to evaluate the efficacy and safety of brazikumab versus placebo in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/19/2021
Locations: Research Site, Tucson, Arizona +1 locations
Conditions: Ulcerative Colitis
Prospective Evaluation of Chronic Pancreatitis for Epidemiologic and Translational Studies, the PROCEED Study
Recruiting
This study gathers information on patients at different stages of chronic pancreatitis to better understand the natural course and risk factors associated with pancreatitis. Chronic pancreatitis is a disease that occurs when the pancreas is inflamed (swollen and irritated) all of the time. It is important for doctors to diagnose chronic pancreatitis in the beginning stages of the disease. Over time, as chronic pancreatitis gets worse, the pancreas may stop working correctly. Since treatment opti... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/22/2021
Locations: Cedars Sinai Medical Center, Los Angeles, California +1 locations
Conditions: Acute Pancreatitis, Chronic Pancreatitis
To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis (LIMBER-313)
Recruiting
The purpose of the study is to compare the efficacy of parsaclisib when combined with ruxolitinb versus placebo combined with ruxolitinib in participants with myelofibrosis.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/24/2021
Locations: CCARE, Fresno, California
Conditions: Myelofibrosis, Primary Myelofibrosis, Post Essential Thrombocythemia Myelofibrosis, Post Polycythemia Vera Myelofibrosis
To Evaluate Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis Who Have Suboptimal Response to Ruxolitinib (LIMBER-304)
Recruiting
The purpose of the study is to compare the efficacy and safety of parsaclisib when combined with ruxolitinb versus placebo combined with ruxolitinib in participants with myelofibrosis who have suboptimal response while receiving ruxolitinib monotherapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/24/2021
Locations: CCARE, Fresno, California
Conditions: Myelofibrosis, Primary Myelofibrosis, Post Essential Thrombocythemia Myelofibrosis, Post Polycythemia Vera Myelofibrosis
Designing a Predictive Tool to Identify Whether a Cancer Patient Has Bacteremia Due to Ceftriaxone-Resistant Escherichia Coli
Recruiting
This study aims to develop a tool to predict whether a cancer patient has bacteria in the blood (bacteremia) due to ceftriaxone-resistant Escherichia (E.) coli. This study may help researchers identify risk factors for ceftriaxone-resistant E. coli bacteremia in cancer patients and improve antibiotic treatment in these patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/28/2021
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Escherichia Coli Infection, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Study to Evaluate The Safety and Efficacy of Balovaptan in Patients With Acute Ischemic Stroke at High Risk of Developing Malignant Brain Edema
Recruiting
This study is designed to evaluate the safety, efficacy, and pharmacokinetics of balovaptan compared with placebo in participants with acute ischemic stroke (AIS) at risk of developing malignant cerebral edema (MCE)
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/04/2022
Locations: University of Alabama At Birmingham, Birmingham, Alabama
Conditions: Acute Ischemic Stroke
Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer
Recruiting
This is a Phase 3, open-label, randomized, clinical trial evaluating the efficacy and safety of gedatolisib plus fulvestrant with or without palbociclib for the treatment of patients with locally advanced or metastatic HR+/HER2- breast cancer following progression on or after CDK4/6 and aromatase inhibitor therapy. Condition or disease: Breast Cancer Intervention/treatment: Drug: Gedatolisib Drug: Palbociclib Drug: Fulvestrant Drug: Alpelisib Phase 3
Gender:
All
Ages:
18 years and above
Trial Updated:
08/02/2022
Locations: University of Alabama at Birmingham, Birmingham, Alabama +1 locations
Conditions: Breast Cancer
CERENOVUS Neurothrombectomy Devices Registry
Recruiting
A post-market registry evaluating the EmboTrap® Revascularization Device and CERENOVUS Large Bore Catheter/ EMBOVAC Aspiration Catheter in acute ischemic stroke patients with confirmed intracranial large vessel occlusion.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/19/2022
Locations: The University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Cerebral Stroke

World-Class Healthcare

CROs offering clinical trials in Houston offer opportunities to fit whatever your preferences are. Check out this short bullet list of available CROs in the area:

  • Moncoa Medical Research
  • Mirobac Laboratories
  • PRA Health Sciences
  • RD Clinical Research
  • Animal Technologies
  • Audie L. Murphy Memorial VA Hospital (STVHCS)
  • Antimicrobial Test Laboratories
  • Abbexa Ltd.

That’s just the tip of the iceberg, check out this link for a more extensive list.


Notable Medical Breakthroughs in Houston

Harris County has 80 hospitals in and of itself, and when you expand into the Greater Houston area, there are over 125. Numerous research facilities are absolutely fundamental to the region, and for anyone interested in paid clinical trials, that means opportunity. Data bears this out; there have been many scientific breakthroughs in medical science from Houston. Several include:

  • The Dacron Graft
  • Mobile Stroke Units
  • Rett Syndrome
  • Gene Discovery
  • Human Hearts Grown In a Lab From Organic Substrates
  • Breakthroughs in Cancer-Fighting Medication

Read more on medical breakthroughs that are centered in Houston here.


Two suburban clusters run their own studies and list separately from Houston:

  • Sugar Land — about 126 recruiting studies: Houston Methodist Sugar Land and private research sites
  • The Woodlands — about 123 recruiting studies: Houston Methodist The Woodlands and Texas Children’s satellite locations

If a Medical Center study is not a fit, these suburban sites sometimes run the same protocols closer to home.

Houston Paid Clinical Trial FAQs

  • How much do paid clinical trials pay in Houston?

    Most outpatient studies in Houston pay $50–$100 per completed visit, plus travel reimbursement. Dedicated Phase 1 units in the metro run higher-paying residential studies. The exact amount appears in the consent form before you enroll.

  • Do I have to be an MD Anderson patient to join a trial there?

    No. MD Anderson accepts referrals and self-referrals for many studies, and some trials recruit healthy volunteers as comparison groups. Each study sets its own eligibility rules, so call the study coordinator listed on the trial record.

  • Where in Houston are most trials located?

    The Texas Medical Center just south of downtown holds the majority: MD Anderson, Baylor College of Medicine, UTHealth, Houston Methodist, and Texas Children’s are all on that campus. Private research sites operate in the suburbs, including Sugar Land, Katy, and The Woodlands.

Advancing Financial Security and Science Simultaneously

Whether you’re a medical student seeking some of the best education in the world, or someone trying to supplement the rising costs of living, you’ll find options in Houston. Houston clinical trials are extensive by necessity, and the history of the region shows they commonly lead to breakthroughs that benefit not only the local community but the world itself. Houston is a global destination for the healthcare industry, and there’s good reason for that.