Paid Clinical Trials in San Antonio

Candace Kastanis

Written by Candace Kastanis

Chemistry B.S. | UC Davis | Clinical Lab Technician

Updated & Fact Checked 7/30/26

Finding Trials in San Antonio

Paid Clinical Trials in San Antonio

San Antonio is one of the best cities in the country for healthy volunteer research. As of July 2026, 990 studies are actively recruiting here, according to ClinicalTrials.gov, and the city hosts a 200-bed Phase 1 clinical pharmacology unit that runs more than 100 studies a year — the kind of residential research that pays the most.

San Antonio alone has 870+ clinical trials presently available, here is more info on Texas trials generally. In the city, there are 1,456,069 documented residents and counting. Studies indicate .005% of the total population (1/200) need to be involved in such trials nationally to meaningfully advance science. So, statistically speaking, you should expect 7,280+ clinical research trial opportunities in San Antonio annually; most of which should be paid (always double-check). When you consider the prevalence of San Antonio medical research organizations designed to advance this science, the availability of such options becomes something very reliable.

Quick Facts: Paid Clinical Trials in San Antonio

  • Actively recruiting studies (July 2026): 990 in San Antonio (ClinicalTrials.gov)
  • Typical compensation: $50–$100 per completed outpatient visit; residential Phase 1 studies pay more (see highest paid clinical trials)
  • Cost to participate: $0 — study care and visits are covered by the sponsor
  • Worth knowing: the city’s 200-bed Phase 1 unit means residential studies paying $3,000–$15,000 run here year-round
  • Statewide options: see paid clinical trials in Texas

Where San Antonio trials actually run

We sampled recruiting San Antonio studies on ClinicalTrials.gov in July 2026. The sites running the most trials:

Research siteTrials sampled
UT Health Science Center at San Antonio64
NEXT Oncology28
Children’s Hospital of San Antonio14
START San Antonio11
Methodist Children’s Hospital12

San Antonio’s mix is unusual: alongside the academic health science center, the city has two well-known early-phase oncology units (NEXT and START) plus a large Phase 1 unit for healthy volunteers. That combination means both patients and healthy participants have options here.

Where Opportunities in Clinical Research Are Expanding Near San Antonio

A CRO is a Clinical Research Organization, and it is usually CROs that offer paid clinical trials for healthy volunteers. What often defines the sort of studies in a local area are its prominent demographic features. To get an idea of what San Antonio looks like, this link explored earlier for the population has surprising insights. Caucasians are 71.9% of locals, 10.13% of residents are two or more races, and black populations comprise 6.78% of San Antonio citizens.

Keep in mind, that many Hispanics are ethnically Caucasian, because Spaniards came from Europe; whereas other Hispanics are ethnically closer to Native Americans. Linguistics and culture aren’t necessarily genetic indicators, and neither is geography.

The median age in the region is 33. About 188k+ locals are senior citizens. Women constitute 50.64% of the local documented population, while males are at 49.36%. There are more women than men locally, most are in the prime of life, and plenty of paid clinical trial opportunities exist in this area for searching residents.

Chromosome 18 Clinical Research Center
Recruiting
Our vision, that of the researchers at the University of Texas Health Science Center at San Antonio, is that every person with a chromosome 18 abnormality will have an autonomous and healthy life. Our mission is to provide families affected by chromosome 18 abnormalities with comprehensive medical and educational information. Our goals are to provide definitive medical and education resources for the families of individuals with chromosome 18 abnormalities; perform and facilitate groundbreaking... Read More
Gender:
ALL
Ages:
All
Trial Updated:
12/03/2024
Locations: University Health Systems Hospital, San Antonio, Texas +1 locations
Conditions: Chromosome Aberrations, Growth Hormone Deficiency, Hypomyelination
Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases
Recruiting
The hypothesis for this study is that a preparative regimen that maximizes host immunosuppression without myeloablation will be well tolerated and sufficient for engraftment of donor hematopoietic cells. It is also to determine major toxicities from these conditioning regimens, within the first 100 days after transplantation.
Gender:
ALL
Ages:
20 years and below
Trial Updated:
07/19/2024
Locations: Phoenix Children's Hospital, Phoenix, Arizona
Conditions: Metabolic Disorders, Hematologic, Immune, or Bone Marrow Disorders, Hemoglobinopathies, Non-malignant Disorders
Role of Neural and Hormonal Regulation Factors on Insulin Secretion After Gastric Bypass Surgery
Recruiting
RYGB (roux-en-y gastric bypass) has been reported to reverse type 2 diabetes (T2DM) immediately after surgery before any significant weight loss. In addition, a growing number of patients have been recognized with life-threatening hyperinsulinemic hypoglycemia several years following their surgery. While the mechanisms by which RYGB improves glucose metabolism or alters islet cell function in patients after RYGB are not understood, recent studies suggest that increased secretion of GI hormones,... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/12/2025
Locations: Texas Diabetes Institute - University Health System, San Antonio, Texas +1 locations
Conditions: Post Bariatricsurgery, Hypoglycemia
Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation
Recruiting
This study will evaluate the safety of infusion of the investigational cord blood units by carefully documenting all infusion-related problems.
Gender:
ALL
Ages:
All
Trial Updated:
04/17/2024
Locations: Children's of Alabama, Birmingham, Alabama
Conditions: Infusion Reactions
Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass
Recruiting
The overall goal of this project is to understand the mechanisms by which gastric bypass surgery improves glucose metabolism. The central hypothesis guiding this project is that the reconfiguration of intestinal transit with the Roux-en-Y will increase the release of insulinotropic GI hormones, termed incretins that improve insulin secretion and glucose metabolism. The study is divided into three specific aims. 1. To determine the role of incretin hormones on insulin secretion in patients with... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/12/2025
Locations: Texas Diabetes Institute - University Health System, San Antonio, Texas +1 locations
Conditions: Post-bariatric Surgery
Prospective Research Assessment in Multiple Myeloma: An Observational Evaluation (PREAMBLE)
Recruiting
The purpose of this study is to assess the clinical effectiveness of all approved multiple myeloma (MM) therapies in the newly-diagnosed (NDMM) and the relapsed/refractory MM (RRMM) settings in real-world clinical practice.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/28/2025
Locations: Local Institution, Birmingham, Alabama +1 locations
Conditions: Multiple Myeloma
Multi-Center Registry for Peripheral Arterial Disease Interventions and Outcomes
Recruiting
XLPAD is an observational study designed to evaluate the effectiveness and use of stent and non-stent based therapies among PAD patients. The study will create a registry that will include entry of procedural and clinical follow-up information into an online data collection software, REDCAP.Data available since Jan 1 2005 will be included in the registry, until 14,000 patients have been included. The primary objectives of this observational registry study are to: 1. Compare stent and non-stent... Read More
Gender:
ALL
Ages:
All
Trial Updated:
12/05/2023
Locations: Arkansas Heart Institute, Little Rock, Arkansas
Conditions: Peripheral Arterial Disease
Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)
Recruiting
This is a multi-center, sequential cohort, open-label, volume and dose escalation study of the safety, tolerability, and distribution of 186RNL given by convection enhanced delivery to patients with recurrent or progressive malignant glioma after standard surgical, radiation, and/or chemotherapy treatment. The study uses a modified Fibonacci dose escalation, followed by an expansion at the maximum tolerated dose (MTD) to determine efficacy. The starting absorbed dose is 1mCi in a volume of 0.660... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Northshore University Hospital, Manhasset, New York
Conditions: Glioma
An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis
Recruiting
The present study D5272C00001 (Legacy # 3151-201-008) seeks to evaluate the efficacy and safety of brazikumab versus placebo in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/19/2021
Locations: Research Site, Tucson, Arizona +1 locations
Conditions: Ulcerative Colitis
A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)
Recruiting
This is a first-in-human study evaluating the anti-T cell immunoglobulin and mucin containing protein-3 (TIM-3) antibody TSR-022. The study will be conducted in 2 parts with Part 1 consisting of dose escalation and Part 2 dose expansion. Part 1 will determine the recommended Phase 2 dose (RP2D) of TSR-022 and Part 2 will evaluate the antitumor activity of TSR-022 in combination with TSR-042 or docetaxel and as monotherapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/14/2024
Locations: GSK Investigational Site, Goodyear, Arizona
Conditions: Neoplasms

A Diverse Population

Though ethnically Caucasian citizens comprise a large majority of the population, there’s still a lot of diversity in terms of mixed ethnicities and cultural backgrounds. Also, because so many locals are young, those asking: “Are there any paid clinical trials near me for healthy volunteers?” will discover that there are many options to consider.

Texas is more affordable than many states, but it is in expansion, and that means inflation is knocking on the door of most homes locally. A paid trial represents a fine tactic for income supplementation, and if you’re thinking about it, demographic data indicates you’re probably a good fit for what’s locally available.


San Antonio CROs Seeking Clinical Research Volunteers That Are Healthy

So where do you find healthy volunteer paid clinical trials? Well, on this website there are quite a few worth considering. Notable among them are the following medical institutions:


Notable Medical Breakthroughs in San Antonio

San Antonio is known for making notable breakthroughs in medicine, and you could be a part of that history. Here are some advances of note:


San Antonio Paid Clinical Trial FAQs

  • How much do paid clinical trials pay in San Antonio?

    Outpatient studies typically pay $50–$100 per completed visit. Residential Phase 1 studies at the city’s clinical pharmacology unit commonly pay $3,000–$15,000 for stays of one to four weeks. The consent form states the exact amount before you enroll.

  • What are Phase 1 studies like in San Antonio?

    You live at the research unit for the length of the study, from a few days to several weeks, with meals and lodging provided. Staff monitor you continuously, and most participants are healthy volunteers rather than patients. Expect frequent blood draws and a strict schedule.

  • Do I need to be a patient somewhere to qualify?

    Not for healthy volunteer studies, which is much of what San Antonio runs. Patient trials at UT Health or the oncology units have condition-specific criteria, but you do not need to be an existing patient to inquire.

Exploring Options For Paid Clinical Trials in San Antonio

At the end of the day, if you’re a San Antonio resident, and you’ve ever found yourself wondering, “are there any paid clinical trials for healthy volunteers near me?”, the answer is a resounding “Yes”.