Paid Clinical Trials in Phoenix

Dr. Ahmed Zayed

Written by Dr. Ahmed Zayed

Board-certified Physician | Graduate w/ Honors Faculty of Medicine | Alexandria, Egypt

Updated & Fact Checked 7/30/26

Phoenix research splits between a major pediatric hospital, Mayo Clinic’s Arizona campus, and a set of cancer centers. As of July 2026, 839 studies are actively recruiting in the city, according to ClinicalTrials.gov.

Clinical Research in Phoenix

Looking for clinical research trials in Phoenix? You are in the right place! Our platform connects anyone who wants to take part in studies and is eager to contribute to medical research. Phoenix, Arizona is a hub of medical innovation, and we are here to help you be a part of it.

Quick Facts: Paid Clinical Trials in Phoenix

  • Actively recruiting studies (July 2026): 839 (ClinicalTrials.gov)
  • Typical compensation: $50–$100 per completed outpatient visit; residential Phase 1 studies pay more (see highest paid clinical trials)
  • Cost to participate: $0 — study care and visits are covered by the sponsor
  • Worth knowing: many metro trials list Scottsdale, Tempe, or Chandler instead of Phoenix — search the suburbs too
  • Statewide options: paid clinical trials in Arizona

Where Phoenix trials actually run

We sampled recruiting Phoenix studies on ClinicalTrials.gov in July 2026. The sites running the most trials:

Research siteTrials sampled
Mayo Clinic Arizona68
Phoenix Children’s Hospital57
Cancer Center at St. Joseph’s (incl. Barrow Neurological)34

Phoenix Children’s is one of the largest pediatric hospitals in the country, and St. Joseph’s hosts Barrow Neurological Institute, which makes the metro stronger in neurology than its size suggests. Note that many studies list Scottsdale, Tempe, Chandler, or Gilbert rather than Phoenix, so searching neighboring cities widens your options.

Clinical Trials For Disease Areas in Phoenix 

Clinical trials are the cornerstone of pioneering treatments and new medications. Our goal is to help researchers find candidates whose contribution can help millions of people live better and more fulfilling lives. It is with your help that we can make that happen.

Between 2020 and 2022, more than $3 billion has been allocated for investment in bioscience infrastructure in Greater Phoenix, solidifying the region as a flourishing center for healthcare education. Luckily, Greater Phoenix hosts some of the most cutting-edge and visionary educational establishments in the nation.

In fact, research centers are frequently conducting clinical trials in Phoenix. They are often related, but not limited to pediatrics, infectious diseases, women’s health, diabetes, obesity, and brain health. 

Medical professionals in Phoenix, Arizona take pride in providing accurate data that can ultimately improve drug development, treatment safety, and efficacy. It is through innovation, excellence, and teamwork that experts take the science of medicine to new heights.

Whether you are interested in new treatments or want to contribute to medical knowledge, we have clinical trials that can suit your needs. Browse the list below to find out more.

Mucopolysaccharidosis I (MPS I) Registry
Recruiting
The Mucopolysaccharidosis I (MPS I) Registry is an ongoing, observational database that tracks the outcomes of patients with MPS I. The data collected by the MPS I Registry will provide information to better characterize the natural history and progression of MPS I as well as the clinical responses of patients receiving enzyme replacement therapy, such as Aldurazyme (Recombinant Human Alpha-L-Iduronidase), or other treatment modalities. The objectives of the Registry are: * To evaluate the lon... Read More
Gender:
ALL
Ages:
All
Trial Updated:
11/19/2024
Locations: Phoenix Children's Hospital- Site Number : 840003, Phoenix, Arizona
Conditions: Mucopolysaccharidosis I (MPS I)
Pompe Pregnancy Sub-Registry
Recruiting
This Sub-registry is a multicenter, international, longitudinal, observational, and voluntary program designed to track pregnancy outcomes for any pregnant woman enrolled in the Pompe Registry, regardless of whether she is receiving disease-specific therapy (such as ERT with alglucosidase alfa or avalglucosidase alfa) and irrespective of the commercial product with which she may be treated. No experimental intervention is given; thus a patient will undergo clinical assessments and receive standa... Read More
Gender:
FEMALE
Ages:
All
Trial Updated:
11/19/2024
Locations: Barrow Neurol Group- Site Number : 840087, Phoenix, Arizona
Conditions: Glycogen Storage Disease Type II (GSD-II), Pompe Disease (Late-onset), Glycogenesis 2 Acid Maltase Deficiency
Collecting Medical Information and Tissue Samples from Patients with Pancreatic Cancer or Other Pancreatic Disorders
Recruiting
RATIONALE: Gathering medical information and collecting and storing samples of blood and tissue to test in the laboratory may help doctors develop better ways to screen people at risk for pancreatic cancer or other pancreatic disorders in the future. PURPOSE: This clinical trial is collecting medical information and tissue samples from patients with pancreatic cancer or other pancreatic disorders.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2025
Locations: Mayo Clinic Hospital in Arizona, Phoenix, Arizona
Conditions: Islet Cell Tumor, Pancreatic Cancer, Pancreatic Disease, Acute Pancreatitis, Chronic Pancreatitis, Hereditary Pancreatitis, Pancreatic Neuroendocrine Carcinoma
Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases
Recruiting
The hypothesis for this study is that a preparative regimen that maximizes host immunosuppression without myeloablation will be well tolerated and sufficient for engraftment of donor hematopoietic cells. It is also to determine major toxicities from these conditioning regimens, within the first 100 days after transplantation.
Gender:
ALL
Ages:
20 years and below
Trial Updated:
07/19/2024
Locations: Phoenix Children's Hospital, Phoenix, Arizona
Conditions: Metabolic Disorders, Hematologic, Immune, or Bone Marrow Disorders, Hemoglobinopathies, Non-malignant Disorders
Cerebral Hemorrhage Risk in Hereditary Hemorrhagic Telangiectasia
Recruiting
This study is one of the three projects of an NIH Rare Disease Clinical Research Consortium. A "consortium" is a group of centres sharing information and resources to perform research. The consortium research focuses on brain blood vessel malformations in three different rare diseases. The focus of this specific study is on Hemorrhagic Telangiectasia (HHT). HHT is a condition characterized by blood vessel malformations, called telangiectasia and arteriovenous malformations (AVMs), occurring in... Read More
Gender:
ALL
Ages:
All
Trial Updated:
03/04/2024
Locations: Barrow Neurological Institute, Phoenix, Arizona
Conditions: Hereditary Hemorrhagic Telangiectasia
Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
Recruiting
Enroll-HD is a longitudinal, observational, multinational study that integrates two former Huntington's disease (HD) registries-REGISTRY in Europe, and COHORT in North America and Australasia-while also expanding to include sites in Latin America. More than 30,000 participants have now enrolled into the study. With annual assessments and no end date, Enroll-HD has built a large and rich database of longitudinal clinical data and biospecimens that form the basis for studies developing tools and b... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: University of Alabama, Birmingham, Alabama
Conditions: Huntington's Disease
Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation
Recruiting
This study will evaluate the safety of infusion of the investigational cord blood units by carefully documenting all infusion-related problems.
Gender:
ALL
Ages:
All
Trial Updated:
04/17/2024
Locations: Children's of Alabama, Birmingham, Alabama +1 locations
Conditions: Infusion Reactions
Vitamin D and Photodynamic Therapy for Treatment of BCC in BCNS
Recruiting
The purpose of this research is to evaluate the use of Photodynamic Therapy (PDT) to treat the multiple basal cell carcinoma (BCC) skin cancers in children and adults with Basal Cell Nevus Syndrome (or who have at least 3 BCC tumors present). In addition, the investigators will test a hypothesis (based upon our extensive preclinical studies in mice) that induction of a transient spike in serum Vitamin D levels through administration of dietary Vitamin D (cholecalciferol; D3) can significantly in... Read More
Gender:
All
Ages:
All
Trial Updated:
11/19/2020
Locations: Medical Dermatology Specilists, Phoenix, Arizona
Conditions: Basal Cell Nevus Syndrome, Basal Cell Carcinoma
Testing Obeticholic Acid (OCA) for Familial Adenomatous Polyposis (FAP)
Recruiting
This is a trial that intends to evaluate the effect of treatment with the drug obeticholic acid in the treatment of the Familial Adenomatous Polyposis condition.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/18/2021
Locations: Mayo Clinic Arizona, Phoenix, Arizona
Conditions: Familial Adenomatous Polyposis
CERENOVUS Neurothrombectomy Devices Registry
Recruiting
A post-market registry evaluating the EmboTrap® Revascularization Device and CERENOVUS Large Bore Catheter/ EMBOVAC Aspiration Catheter in acute ischemic stroke patients with confirmed intracranial large vessel occlusion.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/19/2022
Locations: The University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Cerebral Stroke

Paid trials in Phoenix are a popular option because volunteers get paid for their contributions. Not only can you get financial compensation, but, you can also get paid referrals. So, if you refer a friend you get paid more. Discuss the payment details during your first visit with your study team.

Paid medical studies usually require many outpatient visits. If you stay at the facility, you will get multiple physical exams, blood draws, and general check-ups. Between procedures, you might have time to relax and unwind by playing games, reading, or doing other leisure activities.

Clinical trials are always voluntary. So, if you change your mind, you can always withdraw your consent.  

Clinical Trials For Health Volunteers in Phoenix 

Tried everything else? Then a clinical trial might be exactly what you need. 

When you become a volunteer, you receive treatment under the supervision of research professionals or doctors. Pharmaceutical and biotech companies create these treatments. They choose skilled doctors, often called investigators, to carry out tests on new drugs. 

These tests, known as clinical trials, happen in four stages (Phase I, II, III, and IV). Phase I involves only a few participants, while the later phases have more volunteers. 

If you are interested in applying, check out the feed of trials below. To save you time and effort, we’ve collected the latest clinical trials active in Phoenix, Arizona.

Developing Biomarkers of Dietary Intake: Dose Dependent Measurement of Sugar Intake
Recruiting
Background: Diet is one of the most modifiable behaviors affecting health. But diet assessment measures that are based on self-report can be inaccurate. Researchers want better ways to address the role of diet in chronic disease. They want to see if stable isotopes can be used to better assess what people eat. Objective: To see if stable isotopes can help scientists identify things people eat. Eligibility: Healthy adults ages 18 to 65 Design: Participants will be screened with a medical h... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
07/31/2025
Locations: NIDDK, Phoenix, Phoenix, Arizona
Conditions: Diet Therapy, Healthy Volunteers
The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure
Recruiting
Background: Diet-induced thermogenesis (DIT) is the amount of energy one s body uses to eat food, absorb the nutrients from the food, and process those nutrients. Researchers would like to understand more about how changing the balances of protein, fat, carbohydrates, and total calories in the diet can affect DIT. Objective: To learn how different diets can change a person s DIT. Eligibility: Healthy people aged 18 to 60 years who have not intentionally lost weight in the past 6 months. De... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
07/31/2025
Locations: NIDDK, Phoenix, Phoenix, Arizona
Conditions: Obesity, Normal Physiology, Healthy Volunteers
Variability In Mixed Meal Tests: Fixed Versus Adjusted to Energy Needs Caloric Dose
Recruiting
Background: Researchers use mixed meal tolerance tests (MMTTs) to look at how people s bodies respond to eating a meal. However, researchers do not agree on how to decide the number of calories to give in each meal. Some use fixed meals, which are the same size for everyone, and some use adjusted meals, based on the size of the person s body. Researchers want to know which MMTT is best to use for future research. Objective: To learn how fixed vs adjusted meals affect blood glucose levels in h... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
07/11/2025
Locations: NIDDK, Phoenix, Phoenix, Arizona
Conditions: Obesity, Healthy Volunteer
Bone Mineral Density Agreement Study Between EOSedge™ Versus Traditional DXA
Recruiting
The purpose of this research is to collect medical imaging data to allow for the comparison of bone mineral density measurements from two different types of low-dose x-ray exams, EOSedge and conventional DXA. The main question it aims to answer is: Is there agreement between the calculated T-scores between the 2 different types of x-ray exams?
Gender:
ALL
Ages:
20 years and above
Trial Updated:
02/12/2025
Locations: Honor Health, Phoenix, Arizona
Conditions: Healthy, Indicated for EOSedge Imaging
Increasing Physical Activity Through Social Support and Stress Resilience
Recruiting
The goal of this clinical trial is to learn the effects of technology enhancements when combined with basic education, goal-setting, and self-monitoring to increase physical activity among older adults living alone, experiencing subjective cognitive decline, and currently engaging minimal physical activity (60 minutes or less of moderate to vigorous physical activity). Further, we will examine key psychosocial mechanisms believed to contribute to successful promotion of physical activity, which... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
07/22/2025
Locations: Arizona State University, Phoenix, Arizona
Conditions: Healthy, Subjective Cognitive Decline (SCD), Sedentary Behavior, Social Isolation in Older Adults

Medical Discoveries and Innovation in Phoenix

Phoenix City has one of the best medical facilities in the country. Here, you can get efficient and safe care – all in one place. 

As of 2023, Mayo Clinic Hospital in Arizona has been ranked as the No.1 facility in the area. Founded almost a century ago, the Mayo Clinic has built quite a reputation as an exemplary network of hospitals and clinics that can treat even the most difficult diseases. Today, the non-profit health system is treating over 1 million people every year from 140 different countries. 

Over the past ten years, Downtown Phoenix has also evolved. This progress is evident in the field of bioscience, established institutions, and ongoing construction. 

Phoenix, Arizona is the 5th largest city in the United States and has held the title of fastest-growing for 5 consecutive years. This comes mainly from the influx of healthcare and biotech companies. 

Valley research is spread across several municipalities, each listed separately:

  • Scottsdale — about 388 recruiting studies: Mayo Clinic’s Scottsdale campus and HonorHealth research sites
  • Gilbert — about 150 recruiting studies: Mercy Gilbert and Banner Gateway
  • Chandler — about 135 recruiting studies: Chandler Regional and private research sites
  • Mesa — about 66 recruiting studies: Banner Desert and community sites
  • Tempe — about 42 recruiting studies: ASU-affiliated and private research sites

Scottsdale alone lists nearly half as many studies as Phoenix, so checking the East Valley cities is worth the extra searches.

Phoenix Paid Clinical Trial FAQs

  • How much do paid clinical trials pay here?

    Most outpatient studies pay $50–$100 per completed visit, plus travel reimbursement. Residential Phase 1 studies pay considerably more. The exact amount appears in the consent form before you enroll.

  • Why do some Phoenix-area trials not show up under Phoenix?

    Studies list the exact city of their site. Mayo Clinic has locations in both Phoenix and Scottsdale, and many research sites sit in Tempe, Chandler, Gilbert, or Mesa. Searching those cities alongside Phoenix reveals a substantially larger pool.

  • What conditions are well represented in Phoenix?

    Pediatrics through Phoenix Children’s, neurology through Barrow Neurological Institute at St. Joseph’s, and oncology through Mayo Clinic Arizona and the St. Joseph’s cancer center. Metabolic and diabetes research is also active in the metro.

Why Phoenix Is A Great Place For Clinical Research 

Phoenix City is focused on becoming a national leader in areas like oncology, neurosciences, precision medicine, diagnostics, and bioengineering. And, it is on the right track. 

In 2019, an investment of over $3.7 billion led to the creation of more than 5.7 million square feet of cutting-edge healthcare facilities in the bioscience sector. This remarkable growth has positioned Phoenix at the forefront of life sciences job expansion.

The area also has a diverse population, which makes it a good choice for clinical data. Based on 2021 data, 39.8% of its residents are White, 42.7% are Hispanic, 7.2% are Black, 4% are Asian, 1.6% are American Indian, 0.2% are Native Hawaiian, and 3.9% are multiracial.