Paid Clinical Trials in San Diego

Candace Kastanis

Written by Candace Kastanis

Chemistry B.S. | UC Davis | Clinical Lab Technician

Updated & Fact Checked 7/30/26

Clinical Research For Money in San Diego

Paid Clinical Trials in San Diego

San Diego’s research is split between the city proper and the La Jolla science corridor just north. As of July 2026, 701 studies are actively recruiting in San Diego, according to ClinicalTrials.gov — and another 523 are recruiting in La Jolla, where Scripps, Salk, and much of UC San Diego sit.

In fact, this is true; there are over 644 paid clinical trials for healthy volunteers nearby. Such an opportunity could be within walking distance from where you live. What makes this even more attractive, if you’re looking to supplement your income, is the fact that each trial has multiple volunteers. Expect 5 to 500 participants, depending on the trial. That’s certainly a wide range, but you’ve got to understand the research environment characterizing clinical research today.

It’s estimated .005% of America’s population must be engaged at all times to reach scientific goals in this area. San Diego, including the metro area, has 3.29 million people. That means, on average, you should expect 16,450 locals to be involved in clinical trials at any given time in the city. With 644 studies today, that works out to an average of just over 25 persons per study. So there’s a prime opportunity. Following we’ll explore some more information to help you identify a Clinical Research Organization (CRO) you can explore such opportunities.

Quick Facts: Paid Clinical Trials in San Diego

  • Actively recruiting studies (July 2026): 701 (ClinicalTrials.gov)
  • Typical compensation: $50–$100 per completed outpatient visit; residential Phase 1 studies pay more (see highest paid clinical trials)
  • Cost to participate: $0 — study care and visits are covered by the sponsor
  • Worth knowing: La Jolla has about 523 recruiting studies of its own — search it alongside San Diego
  • Statewide options: paid clinical trials in California

Where San Diego trials actually run

We sampled recruiting San Diego studies on ClinicalTrials.gov in July 2026. The sites running the most trials:

Research siteTrials sampled
UC San Diego (incl. Moores Cancer Center)51
Rady Children’s Hospital48
Kaiser Permanente San Diego19
UC San Diego Medical Center, Hillcrest19

La Jolla is the detail that matters most here. Scripps Research, the Salk Institute, and several UC San Diego facilities list La Jolla as their city, so a search limited to “San Diego” misses roughly 523 additional recruiting studies a short drive up the coast.

Notable Opportunities in California’s Southernmost Metropolis

Demographic indicators help narrow down where someone on the hunt can find paid clinical trials nearby for healthy volunteers. There are a few reasons for this; in a nutshell, CROs need to calibrate studies to match available participants. It would be ludicrous to study Caucasian longevity in Japan; for such studies, Caucasian populations would be needed. So what does census data reveal about San Diego demographics?

Caucasians are at 61.95% of the population, Asians are at 17.25%, 7.77% of the population have more than one race in their ethnic background, and 6.09% are of African descent. Further demographic data from the same source indicates men are, on average, 35.2 years old, women are 36.2, and represent a slight reduction in numbers overall, with only 49.46% of residents being women, and 50.54% being men.

Follow-up Visit of High Risk Infants
Recruiting
The NICHD Neonatal Research Network's Follow-Up study is a multi-center cohort in which surviving extremely low birth-weight infants born in participating network centers receive neurodevelopmental, neurosensory and functional assessments at 22-26 months corrected age (Infants born prior to July 1, 2012 were seen at 18-22 months corrected age). Data regarding pregnancy and neonatal outcome are collected prospectively. The goal is to identify potential maternal and neonatal risk factors that may... Read More
Gender:
ALL
Ages:
Between 18 months and 26 months
Trial Updated:
02/11/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama +1 locations
Conditions: Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Consent for Use of Stored Patient Specimens for Future Testing
Recruiting
The purpose of this study is to obtain informed consent to use stored human biological materials (HBM) (e.g., blood and other tissues) for future studies that may include genetic testing.
Gender:
ALL
Ages:
All
Trial Updated:
09/20/2024
Locations: Univ of Southern California / LA County USC Med Ctr, Los Angeles, California
Conditions: HIV Infections
Generic Database of Very Low Birth Weight Infants
Recruiting
The Generic Database (GDB) is a registry of very low birth weight infants born alive in NICHD Neonatal Research Network (NRN) centers. The GDB collects observational baseline data on both mothers and infants, and the therapies used and outcomes of the infants. The information collected is not specific to a disease or treatment (i.e., it is "generic"). Data are analyzed to find associations and trends between baseline information, treatments, and infant outcome, and to develop future NRN trials.
Gender:
ALL
Ages:
14 days and below
Trial Updated:
02/11/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama +1 locations
Conditions: Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Mucopolysaccharidosis I (MPS I) Registry
Recruiting
The Mucopolysaccharidosis I (MPS I) Registry is an ongoing, observational database that tracks the outcomes of patients with MPS I. The data collected by the MPS I Registry will provide information to better characterize the natural history and progression of MPS I as well as the clinical responses of patients receiving enzyme replacement therapy, such as Aldurazyme (Recombinant Human Alpha-L-Iduronidase), or other treatment modalities. The objectives of the Registry are: * To evaluate the lon... Read More
Gender:
ALL
Ages:
All
Trial Updated:
11/19/2024
Locations: Phoenix Children's Hospital- Site Number : 840003, Phoenix, Arizona
Conditions: Mucopolysaccharidosis I (MPS I)
Prospective Database Registry Study of Scoliosis in Children With Cerebral Palsy
Recruiting
The purpose of this study is to determine the radiographic and clinical outcomes of Scoliosis surgical and non-operative treatment in patients with Cerebral Palsy.
Gender:
ALL
Ages:
Between 8 years and 21 years
Trial Updated:
11/20/2023
Locations: Rady Children's Hospital, San Diego, California
Conditions: Cerebral Palsy, Scoliosis
Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases
Recruiting
The hypothesis for this study is that a preparative regimen that maximizes host immunosuppression without myeloablation will be well tolerated and sufficient for engraftment of donor hematopoietic cells. It is also to determine major toxicities from these conditioning regimens, within the first 100 days after transplantation.
Gender:
ALL
Ages:
20 years and below
Trial Updated:
07/19/2024
Locations: Phoenix Children's Hospital, Phoenix, Arizona
Conditions: Metabolic Disorders, Hematologic, Immune, or Bone Marrow Disorders, Hemoglobinopathies, Non-malignant Disorders
Registry Study for Radiation Therapy Outcomes
Recruiting
The purpose of this research study is to collect and analyze information from patients being treated with various forms of radiation therapy.
Gender:
ALL
Ages:
All
Trial Updated:
05/30/2024
Locations: Mayo Clinic, Scottsdale, Arizona
Conditions: Neoplasms
Specimen Collection from Pregnant Women At Increased Risk for Fetal Aneuploidy
Recruiting
The specimen collection is designed for the purpose of the development of a noninvasive prenatal test for T21.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
10/11/2024
Locations: University of Alabama Birmingham, Birmingham, Alabama +3 locations
Conditions: Down Syndrome, Fetal Aneuploidy
Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
Recruiting
Enroll-HD is a longitudinal, observational, multinational study that integrates two former Huntington's disease (HD) registries-REGISTRY in Europe, and COHORT in North America and Australasia-while also expanding to include sites in Latin America. More than 30,000 participants have now enrolled into the study. With annual assessments and no end date, Enroll-HD has built a large and rich database of longitudinal clinical data and biospecimens that form the basis for studies developing tools and b... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: University of Alabama, Birmingham, Alabama
Conditions: Huntington's Disease
Clinical Trial Evaluating the Efficacy, Safety, and Tolerability of Cariprazine in a Dose-Reduction Paradigm in the Prevention of Relapse in Patients With Schizophrenia
Recruiting
To evaluate the efficacy and safety of cariprazine at a target dose of 4.5 mg/d compared with placebo in prevention of relapse in patients with schizophrenia To evaluate the efficacy and safety of cariprazine at a target dose of 3.0 mg/d compared with placebo in prevention of relapse in patients with schizophrenia who were initially stabilized on a target dose of 4.5 mg/d
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
08/17/2020
Locations: Pillar Clinical Research, Bentonville, Arkansas +1 locations
Conditions: Schizophrenia

Exploring San Diego Diversity to Identify Paid Trail Opportunities

The lion’s share of local opportunities will be men in their mid-thirties who are either Caucasian, Hispanic, or Asian, with Hispanic populations often included in Caucasian statistics owing to ethnic roots. This will be followed by females in the same category.

There will be paid clinical trials for healthy volunteers who occupy other demographic areas of the local population as well, you might just have to do a little more research.

We have compiled the following list of paid clinical trials for healthy volunteers, click the Search All button at the bottom to find more:


Multiple San Diego CROs Provide Opportunities for Healthy Participants

Here are several options for healthy volunteer-paid clinical trials in San Diego. These will give you an idea of what to look for, and where CRO opportunities may be found:


Notable Breakthroughs Centered in San Diego

You’re in good company if you become involved in CRO opportunities in San Diego, the city is well-known for its medical breakthroughs. Consider the following achievements of the city:


Some of the biggest research operations near San Diego list their own city rather than San Diego, so a city-only search misses them. These are the ones worth checking:

  • La Jolla — about 523 recruiting studies: Scripps Research, the Salk Institute, and several UC San Diego facilities sit here, about 15 minutes up the coast from downtown

If a study looks right but lists La Jolla, it is usually no farther from central San Diego than a cross-town commute.

San Diego Paid Clinical Trial FAQs

  • How much do paid clinical trials pay here?

    Most outpatient studies pay $50–$100 per completed visit, plus travel reimbursement. Residential Phase 1 studies pay considerably more. The exact amount appears in the consent form before you enroll.

  • Why should I search La Jolla separately?

    Studies list the exact city of their site, and La Jolla is a distinct entry from San Diego even though it sits within the city limits. Scripps, Salk, and parts of UC San Diego list La Jolla, which accounts for roughly 523 recruiting studies not shown in a San Diego-only search.

  • Are there pediatric trials in San Diego?

    Yes. Rady Children’s Hospital is one of the most active research sites in the county and runs studies across many pediatric specialties. Parental consent is required, and children old enough to understand also give their own assent.

Finding Nearby Clinical Research Trial Opportunities

The bottom line is, that if you’re one of the 3.29 million residents of San Diego’s metropolitan area, there are thousands of CRO opportunities available that can provide additional income for you. Hopefully, the information here helps direct your search.