Paid Clinical Trials in Pittsburgh

Candace Kastanis

Written by Candace Kastanis

Chemistry B.S. | UC Davis | Clinical Lab Technician

Updated & Fact Checked 7/30/26

Quick Facts: Paid Clinical Trials in Pittsburgh

  • Actively recruiting studies (July 2026): 1,205 (ClinicalTrials.gov)
  • Typical compensation: $50–$100 per completed outpatient visit; residential Phase 1 studies pay more (see highest paid clinical trials)
  • Cost to participate: $0 — study care and visits are covered by the sponsor
  • Worth knowing: UPMC runs trials across dozens of regional locations, so ask which sites a study uses before assuming you must travel to Oakland
  • Statewide options: paid clinical trials in Pennsylvania

Where Pittsburgh trials actually run

We sampled recruiting Pittsburgh studies on ClinicalTrials.gov in July 2026. The sites running the most trials:

Research siteTrials sampled
University of Pittsburgh and UPMC (incl. Hillman Cancer Center)207
UPMC Children’s Hospital of Pittsburgh28
Allegheny General Hospital27

Because UPMC operates dozens of hospitals and clinics around the region, a study listed in Pittsburgh may actually run at a location closer to you. Ask the coordinator which UPMC sites are participating. Allegheny Health Network provides an alternative if a UPMC study is not a fit.

Pittsburgh Paid Clinical Trial FAQs

  • How much do paid clinical trials pay here?

    Most outpatient studies pay $50–$100 per completed visit, plus travel reimbursement. Residential Phase 1 studies pay considerably more. The exact amount appears in the consent form before you enroll.

  • Where in Pittsburgh are most trials located?

    The Oakland neighborhood holds the core: UPMC Presbyterian, Hillman Cancer Center, Children’s Hospital, and the University of Pittsburgh campus. Allegheny General is on the North Side, and UPMC community hospitals run studies throughout the region.

  • Can I join a UPMC trial at a hospital near me?

    Sometimes. Many UPMC studies enroll at multiple system locations rather than only in Oakland. When you contact the study coordinator, ask which participating sites are closest to you.

Healthy Volunteer Research Opportunities

Paid Clinical Trials in Pennsylvania

Pittsburgh’s research runs largely through one very large system. As of July 2026, 1,205 studies are actively recruiting in the city, according to ClinicalTrials.gov, and UPMC together with the University of Pittsburgh accounts for most of them.

In order to determine what might be available for you, there are three additional numbers to consider. You want to know how much work needs to be done; what’s the “demand” for CRO discoveries. Experts say 1 out of 200 people in the US need to be involved in such trials continuously. The next two numbers are the population of Pittsburgh proper, and the surrounding CSA.

Pittsburgh proper has approximately 302,425 people, while the surrounding CSA has 2,635,228 as of mid-2016. With these numbers, we can conclude there are between 17 and 153 individual opportunities per CRO in the area. Likely, there will be more options at each CRO, this is just the average range the stats indicate. Demographic information helps us narrow your potential opportunities down further.

Demographic Data Indicates Trial Availability
To further narrow down what paid clinical trials for healthy volunteers are available in Pittsburgh, we want to look at the city’s demographics. Now, these numbers are centered around the 302k+ people living in Pittsburgh proper, rather than the surrounding area, but trends in CRO trials will likely base volunteer opportunities on this data. Locally, 66.37% of the population are Caucasian, 22.98% are of African descent, Asians are at 5.83%, there are 3.62% of the population who are two or more races, and other demographic stats are statistically negligible. The median age is 32.6, 51.01% of the population are female, 48.99% are male.

Consent for Use of Stored Patient Specimens for Future Testing
Recruiting
The purpose of this study is to obtain informed consent to use stored human biological materials (HBM) (e.g., blood and other tissues) for future studies that may include genetic testing.
Gender:
ALL
Ages:
All
Trial Updated:
09/20/2024
Locations: Univ of Southern California / LA County USC Med Ctr, Los Angeles, California
Conditions: HIV Infections
Mucopolysaccharidosis I (MPS I) Registry
Recruiting
The Mucopolysaccharidosis I (MPS I) Registry is an ongoing, observational database that tracks the outcomes of patients with MPS I. The data collected by the MPS I Registry will provide information to better characterize the natural history and progression of MPS I as well as the clinical responses of patients receiving enzyme replacement therapy, such as Aldurazyme (Recombinant Human Alpha-L-Iduronidase), or other treatment modalities. The objectives of the Registry are: * To evaluate the lon... Read More
Gender:
ALL
Ages:
All
Trial Updated:
11/19/2024
Locations: Phoenix Children's Hospital- Site Number : 840003, Phoenix, Arizona
Conditions: Mucopolysaccharidosis I (MPS I)
Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema, and Atopic Dermatitis Research
Recruiting
This is a tissue, urine, and blood banking protocol for cutaneous t-cell lymphoma (CTCL), eczema, and atopic dermatitis patients for current and future research.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/06/2025
Locations: University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
Conditions: Cutaneous T-cell Lymphoma, Sezary Syndrome, Mycosis Fungoides, Eczema, Atopic Dermatitis
Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis (IPF)
Recruiting
The purposes of this study are: * to determine if there are specific genetic traits that might explain why patients have developed pulmonary fibrosis; * to determine if specific genetic traits account for differing patterns of inflammation and scar tissue that has formed in the patient's lungs.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/31/2024
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Pulmonary Fibrosis
Dorothy P. and Richard P. Simmons Center for ILD Research Registry
Recruiting
The purpose of this study is to place past, current, and future medical record information into the UPMC Simmons Center for Interstitial Lung Disease Research Registry.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/31/2024
Locations: Michelle F MacPherson, Pittsburgh, Pennsylvania
Conditions: Lung Diseases, Interstitial
Detection of Genetic Markers of Lung Cancer
Recruiting
The purpose of this research study is to determine the genetic changes and immunologic changes that are involved in the development and progression of bronchogenic lung cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/22/2024
Locations: Hillman Cancer Center, Pittsburgh, Pennsylvania
Conditions: Lung Cancer
Prospective Evaluation of Chronic Pancreatitis for Epidemiologic and Translational Studies, the PROCEED Study
Recruiting
This study gathers information on patients at different stages of chronic pancreatitis to better understand the natural course and risk factors associated with pancreatitis. Chronic pancreatitis is a disease that occurs when the pancreas is inflamed (swollen and irritated) all of the time. It is important for doctors to diagnose chronic pancreatitis in the beginning stages of the disease. Over time, as chronic pancreatitis gets worse, the pancreas may stop working correctly. Since treatment opti... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/22/2021
Locations: Cedars Sinai Medical Center, Los Angeles, California
Conditions: Acute Pancreatitis, Chronic Pancreatitis
Study of Acalabrutinib (ACP-196) in Combination With Venetoclax (ABT-199), With and Without Obinutuzumab (GA101) Versus Chemoimmunotherapy for Previously Untreated CLL
Recruiting
The purpose of this study is to evaluate the efficacy and safety of acalabrutinib in combination with venetoclax and acalabrutinib in combination with venetoclax with and without obinutuzumab compared to chemoimmunotherapy in subjects with previously untreated CLL.
Gender:
All
Ages:
Between 18 years and 130 years
Trial Updated:
01/14/2022
Locations: Research Site, Fountain Valley, California +1 locations
Conditions: Chronic Lymphocytic Leukemia
Qualification for Cone-Optogenetics
Recruiting
This study aims to prepare for the first-in-human clinical trial of cone optogenetics vision restoration. As a first step, this worldwide multicenter ocular imaging study (EyeConic Study) is performed to identify eligible patients.
Gender:
All
Ages:
All
Trial Updated:
01/19/2022
Locations: University of California San Francisco, Department of Ophthalmology, San Francisco, California
Conditions: Retinal Dystrophies
A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)
Recruiting
This is a first-in-human study evaluating the anti-T cell immunoglobulin and mucin containing protein-3 (TIM-3) antibody TSR-022. The study will be conducted in 2 parts with Part 1 consisting of dose escalation and Part 2 dose expansion. Part 1 will determine the recommended Phase 2 dose (RP2D) of TSR-022 and Part 2 will evaluate the antitumor activity of TSR-022 in combination with TSR-042 or docetaxel and as monotherapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/14/2024
Locations: GSK Investigational Site, Goodyear, Arizona
Conditions: Neoplasms

Interpreting Pittsburgh Demographic Information to Find Paid Trials
So the preponderance of paid clinical trials for healthy volunteers will be geared toward white and black girls in their early thirties, followed by white and black men in the same category. That said, it’s worth noting that any clinical trial benefits more when its findings have a broadly applicable relevance to the general population. So only in niche situations will ethnic background be a delineating agent. For the most part, CROs want more diversity, not less.

Pittsburgh CROs Healthy Participants Can Explore
Here’s a selection of three CROs that may offer healthy volunteer paid clinical trials. These can help you figure out what’s locally available, and what to look for:

Medical Trends in Pittsburgh Advancing Science
Beyond the monetary angle, historical significance rests in the discoveries of CROs. Pittsburgh is actually known, in part, for its medical discoveries. Being involved in clinical research through CROs might give you the opportunity to be involved in medical innovations such as the following:

Potential Pittsburgh Trials For Local Healthy Volunteers
The bottom line is, you’ve got a lot of options when it comes to CROs in Pittsburgh. Truly, if you’re interested, beyond making a little money you can be involved in the sort of history that advances medical science. Investigate this; you might be surprised.