Paid Clinical Trials in San Jose

Dr. Ahmed Zayed

Written by Dr. Ahmed Zayed

Board-certified Physician | Graduate w/ Honors Faculty of Medicine | Alexandria, Egypt

Updated & Fact Checked 7/30/26

San Jose has surprisingly few trials of its own for a city its size. As of July 2026, 86 studies are actively recruiting here, according to ClinicalTrials.gov — because South Bay research is concentrated a few miles north at Stanford, which lists Palo Alto and Stanford rather than San Jose.

Clinical Research in San Jose

San Jose is a convenient location for medical research scientists, local doctors, and biotech companies to expand current research or start new projects. 

When an organization or company wants to explore a new medication or procedure, they need to carry out thorough research to assess its safety and effectiveness. This process usually takes years of testing in labs. Once experts determine its safety, they are ready to do clinical trials. 

Our platform is here to streamline the entire process. With our help, you can get access to clinical trials near you.

Quick Facts: Paid Clinical Trials in San Jose

  • Actively recruiting studies (July 2026): 86 (ClinicalTrials.gov)
  • Typical compensation: $50–$100 per completed outpatient visit; residential Phase 1 studies pay more (see highest paid clinical trials)
  • Cost to participate: $0 — study care and visits are covered by the sponsor
  • Worth knowing: Palo Alto and Stanford together list over 900 recruiting studies — a short drive from San Jose
  • Statewide options: paid clinical trials in California

Where San Jose trials actually run

We sampled recruiting San Jose studies on ClinicalTrials.gov in July 2026. The sites running the most trials:

Research siteTrials sampled
Kaiser Permanente Santa Teresa, San Jose41
Stanford Cancer Center South Bay11
Private research sites (neurology, urology)7

The practical approach in the South Bay is to search Palo Alto and Stanford as well: those two entries carry more than 900 recruiting studies between them, roughly ten times what San Jose lists. Kaiser Permanente Santa Teresa is the largest site inside San Jose itself, and Stanford operates a South Bay cancer center in the city.

Clinical Trials For Disease Areas in San Jose 

In San Jose, California, clinical research trials cover a wide range of disease areas. These may include but are not limited to gastroenterology, mental health research studies, holistic medicine, oncology, endocrinology, infectious diseases, and more.

Health Care-Stanford Hospital is the No.1 institution in San Jose, California. Nationally acclaimed, it boasts an impressive ranking in 11 specialized medical fields and demonstrates exceptional performance in an additional specialty, as well as across 19 critical procedures and conditions. 

El Camino Health-Mountain View is another high-performing medical facility. The teams there run studies across several specialties. They are one of the many facilities that provide the latest research studies. 

If you want to be a part of something big and provide data that can lead to future medical advancements, apply for clinical trials today!

Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)
Recruiting
This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important for tumor cell growth and progression. Crizotinib may stop the growth of tumor cells by blocking the ALK protein from working. Crizotinib may be an effective treatment for patients with non-sma... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/29/2024
Locations: University of Alabama at Birmingham Cancer Center, Birmingham, Alabama
Conditions: ALK Gene Rearrangement, ALK Gene Translocation, ALK Positive, Stage IB Non-Small Cell Lung Carcinoma AJCC v7, Stage II Non-Small Cell Lung Cancer AJCC v7, Stage IIA Non-Small Cell Lung Carcinoma AJCC v7, Stage IIB Non-Small Cell Lung Carcinoma AJCC v7, Stage IIIA Non-Small Cell Lung Cancer AJCC v7
Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer
Recruiting
This phase III trial studies how well standard systemic therapy with or without definitive treatment (prostate removal surgery or radiation therapy) works in treating participants with prostate cancer that has spread to other places in the body. Addition of prostate removal surgery or radiation therapy to standard systemic therapy for prostate cancer may lower the chance of the cancer growing or spreading.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
08/14/2024
Locations: Banner MD Anderson Cancer Center, Gilbert, Arizona
Conditions: Castration Levels of Testosterone, Metastatic Prostatic Adenocarcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Recruiting
This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruing simultaneously to a multi-sub-study hybrid Master Protocol (Lung-MAP). The type of cancer trait (biomarker) will determine to which sub-study, within this protocol, a participant will be assigned to compare new targeted cancer therapy, designed to block the growth and spread of cancer, or combinations to standard of... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/12/2025
Locations: Veterans Administration Medical Center - Birmingham, Birmingham, Alabama
Conditions: Previously Treated Non-Small Cell Lung Cancer
Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
Recruiting
Patients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin. There is evidence that less radical margins of excision may be just as safe. This is a randomised controlled trial of 1 cm versus 2 cm margin of excision of the primary lesion for adult patients with stage II primary invasive cutaneous melanomas (AJCC 8th edition) to determine differences in disease-free survival. A reduction in margins is expected to improve patient quality of... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/25/2024
Locations: University of South Alabama Mitchell Cancer Institute, Mobile, Alabama
Conditions: Cutaneous Melanoma, Stage II
S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration
Recruiting
Patients are enrolled to screening (Reg Step 1) prior to or after ASCT but prior to Reg Step 2. Patients are followed until they will begin Maintenance and then registered to Reg Step 2 (first randomization). Patients are randomized between Lenalidomide for 2 years and Lenalidomide + Daratumumab/rHuPH20. After 2 years of Maintenance, MRD is assessed to guide further therapy. MRD-positive patients will continue with the assigned treatment. MRD-negative patients will be further randomized (Reg Ste... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/21/2024
Locations: Anchorage Associates in Radiation Medicine, Anchorage, Alaska
Conditions: Multiple Myeloma
T-DM1 and Tucatinib Compared with T-DM1 Alone in Preventing Relapses in People with High Risk HER2-Positive Breast Cancer, the CompassHER2 RD Trial
Recruiting
This phase III trial studies how well trastuzumab emtansine (T-DM1) and tucatinib work in preventing breast cancer from coming back (relapsing) in patients with high risk, HER2 positive breast cancer. T-DM1 is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug, called DM1. Trastuzumab is a form of targeted therapy because it attaches to specific molecules (receptors) on the surface of cancer cells, known as HER2 receptors, and delivers DM1 to kill them. Tucatinib may stop t... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/09/2025
Locations: University of Alabama at Birmingham Cancer Center, Birmingham, Alabama +1 locations
Conditions: Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Anatomic Stage IIIC Breast Cancer AJCC v8, HER2 Positive Breast Carcinoma, Invasive Breast Carcinoma, Multifocal Breast Carcinoma, Prognostic Stage I Breast Cancer AJCC v8, Prognostic Stage IA Breast Cancer AJCC v8, Prognostic Stage IB Breast Cancer AJCC v8, Prognostic Stage II Breast Cancer AJCC v8, Prognostic Stage IIA Breast Cancer AJCC v8, Prognostic Stage IIB Breast Cancer AJCC v8, Prognostic Stage III Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8, Prognostic Stage IIIB Breast Cancer AJCC v8, Prognostic Stage IIIC Breast Cancer AJCC v8, Synchronous Bilateral Breast Carcinoma
Effect of Prehabilitation on Surgical Outcomes of Abdominally-based Plastic Surgery Procedures
Recruiting
The purpose of this study is to determine whether a program to optimize patient physical fitness and nutrition ("prehabilitation") prior to and after plastic surgery involving the abdomen improves surgical outcomes. The investigators hope to determine how a multimodal peri-operative prehabilitation program can be most effective in engaging and motivating patients to physically and mentally get ready for an abdominally-based plastic surgery operation. The overall goal is to determine if this prog... Read More
Gender:
ALL
Ages:
19 years and above
Trial Updated:
12/14/2021
Locations: Stanford Cancer Center South Bay, San Jose, California
Conditions: Ventral Hernia, Panniculus, Abdominoplasty, Flap Reconstruction
A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
Recruiting
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis histological stage F2 or F3
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: Pinnacle Research Group, Anniston, Alabama
Conditions: NASH - Nonalcoholic Steatohepatitis
Mechanical Coring to Achieve Directional Skin Tightening
Recruiting
The objective of this clinical study is to evaluate the safety and efficacy of mechanical coring for directional skin tightening. This study is a prospective, up to 3 center, multiple skin treatment area study of the safety and efficacy of mechanical coring with directional closure to achieve directional skin tightening.
Gender:
ALL
Ages:
Between 30 years and 70 years
Trial Updated:
02/13/2024
Locations: Berman Skin Institute, Los Altos, California
Conditions: Skin Tightening, Healthy Volunteers
Evaluating the Effects of Tasimelteon in Individuals With Autism Spectrum Disorder (ASD) and Sleep Disturbances
Recruiting
This is a multicenter, open-label study to evaluate the efficacy and safety of a daily single oral dose of tasimelteon in treating sleep disturbances in pediatric and adult participants with ASD.
Gender:
ALL
Ages:
Between 2 years and 65 years
Trial Updated:
03/19/2024
Locations: Vanda Investigational Site, San Jose, California
Conditions: Autism Spectrum Disorder, Sleep Disorder, Neurological Disorder, Sleep Disturbance

Paid clinical trials for medical research usually provide payments of about $50 to $300 per day, with the potential to earn thousands of dollars. So, it shouldn’t come as a surprise that about 5% of students make money by taking part in clinical trials. 

Most paid clinical trials in San Jose, have specific requirements. You need to meet these requirements to be able to apply. For example, if a drug is being tested for a specific illness, like diabetes, then you need to be diabetic. 

Other trials, however, may ask that you be in relatively good health, and avoid drinking, and smoking. It depends on the type of clinical trial you participate in. Also, the riskier the trial, the bigger the pay. So, this is something to think about before applying.

Clinical Trials For Health Volunteers in San Jose 

Choosing to apply for a clinical trial is a personal decision. As a health volunteer, you need to know your options and learn about the trial research and goals. You might want to consult with your friends, family, and doctor before applying.

Through research studies, experts learn how the body works, how diseases develop, and ways to handle treatment. But, the best treatment approaches are found after years of studies. By taking part, you help experts gain valuable insight that can have long-term effects.

The goal is simple: use science to improve people’s lives. But, to do that, we need your help! Check the list below and find a clinical trial that can accommodate your needs.

Mechanical Coring to Achieve Directional Skin Tightening
Recruiting
The objective of this clinical study is to evaluate the safety and efficacy of mechanical coring for directional skin tightening. This study is a prospective, up to 3 center, multiple skin treatment area study of the safety and efficacy of mechanical coring with directional closure to achieve directional skin tightening.
Gender:
ALL
Ages:
Between 30 years and 70 years
Trial Updated:
02/13/2024
Locations: Berman Skin Institute, Los Altos, California
Conditions: Skin Tightening, Healthy Volunteers

Medical Discoveries and Innovation in San Jose

Technology can save lives. San Jose California is a thriving ecosystem of world-class research institutions, visionary experts, and cutting-edge biotechnology firms, which put the city at the forefront of medical innovation.

The field of biotechnology and life sciences is a perfect example. San Jose is one of the major cities within the San Francisco Bay Area. It’s located at the southern end of the Bay Area and is often referred to as the “Capital of Silicon Valley” due to its central role in the technology and innovation sector.

The city is home to many facilities that research areas such as genomics, personalized medicine, and drug development. In fact, the San Francisco Bay Area has more biotechnology firms than any other location around the world. This makes it a key focus for companies and industry experts within the valley. 

South Bay research clusters north of San Jose, and each city lists separately:

  • Palo Alto — about 575 recruiting studies: Stanford Health Care and the Palo Alto VA
  • Stanford — about 343 recruiting studies: the Stanford School of Medicine campus
  • Santa Clara — about 50 recruiting studies: Kaiser Permanente Santa Clara
  • Mountain View — about 39 recruiting studies: El Camino Health and private research sites

Those four areas list roughly a thousand recruiting studies between them, compared with 86 inside San Jose.

San Jose Paid Clinical Trial FAQs

  • How much do paid clinical trials pay here?

    Most outpatient studies pay $50–$100 per completed visit, plus travel reimbursement. Residential Phase 1 studies pay considerably more. The exact amount appears in the consent form before you enroll.

  • Why are there so few trials listed in San Jose?

    South Bay research is concentrated at Stanford, whose sites list Palo Alto or Stanford as their city rather than San Jose. San Jose itself has Kaiser Permanente Santa Teresa and a Stanford satellite cancer center, plus a handful of private research sites.

  • Where should I look instead?

    Search Palo Alto and Stanford, which together list more than 900 recruiting studies, and consider San Francisco for UCSF studies. Caltrain connects San Jose to both, and many studies reimburse travel costs.

Why San Jose Is A Great Place For Clinical Research 

San Jose boasts a diverse and multicultural population, providing a broad pool of potential participants for clinical trials. 

Recent reports show that 34.83% of the city’s residents are White, 37.5% are Asian, 13.04% are from other races, 10.44% are Multiracial, 2.97% are Black, 0.76% are Native American, and 0.46% are Native Hawaiian. 

Sponsors need that range of participants so results apply broadly.